Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 302059..302859 Replicon chromosome
Accession NZ_CP110258
Organism Escherichia albertii strain KBSW50i

Toxin (Protein)


Gene name ataT Uniprot ID B1EHN9
Locus tag N6N69_RS01450 Protein ID WP_000342453.1
Coordinates 302332..302859 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag N6N69_RS01445 Protein ID WP_098401847.1
Coordinates 302059..302325 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N6N69_RS01420 297780..298634 - 855 WP_105227881.1 PTS system mannose/fructose/sorbose family transporter subunit IID -
N6N69_RS01425 298627..299373 - 747 WP_000151888.1 PTS sugar transporter subunit IIC -
N6N69_RS01430 299390..299875 - 486 WP_000029259.1 PTS sugar transporter subunit IIB -
N6N69_RS01435 299882..300283 - 402 WP_262930538.1 PTS sugar transporter subunit IIA -
N6N69_RS01440 300806..301909 + 1104 WP_105227877.1 branched chain amino acid ABC transporter substrate-binding protein LivJ -
N6N69_RS01445 302059..302325 + 267 WP_098401847.1 type II toxin-antitoxin system antitoxin AtaR Antitoxin
N6N69_RS01450 302332..302859 + 528 WP_000342453.1 type II toxin-antitoxin system toxin acetyltransferase AtaT Toxin
N6N69_RS01455 302856..303239 - 384 WP_103054016.1 aspartate 1-decarboxylase autocleavage activator PanM -
N6N69_RS01460 303663..304772 + 1110 WP_000827693.1 high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK -
N6N69_RS01465 304820..305746 + 927 WP_001295111.1 high-affinity branched-chain amino acid ABC transporter permease LivH -
N6N69_RS01470 305743..307020 + 1278 WP_059228517.1 branched chain amino acid ABC transporter permease LivM -
N6N69_RS01475 307017..307784 + 768 WP_000082101.1 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(88-150)

Antitoxin

Vibrio phage ICP1, Orf50

(8-86)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19676.58 Da        Isoelectric Point: 6.9585

>T263478 WP_000342453.1 NZ_CP110258:302332-302859 [Escherichia albertii]
MDDLTIEILTDDADYDLQRFDCGEEALNLFLTTHLVRQHRNKILRAYILCRNTPERQVLGYYTLSGSCFERAALPSKSKQ
KKIPYKNIPSVTLGRLAIDRSLQGQGWGATLVAHAMKVVWSASLAVGIHGLFVEALNEKAHTFYQSLGFIPLVGENENAL
FFPTKSIELLFTQSD

Download         Length: 528 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9919.34 Da        Isoelectric Point: 10.0862

>AT263478 WP_098401847.1 NZ_CP110258:302059-302325 [Escherichia albertii]
MSAVKKQRIDLRLTDDDKSMIEEAAAISNQSVSQFMLNSASQRAAEVIEQNRRMILNEESWTRVMDALSNPPSPGEKLKR
AAKRLQGM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References