Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 30893..31386 Replicon plasmid unnamed4
Accession NZ_CP110241
Organism Vagococcus sp. STAA25

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OL235_RS10890 Protein ID WP_275470171.1
Coordinates 31111..31386 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OL235_RS10885 Protein ID WP_275470170.1
Coordinates 30893..31114 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OL235_RS10865 (OL235_10865) 29018..29224 + 207 WP_275470165.1 hypothetical protein -
OL235_RS10870 (OL235_10870) 29224..29478 + 255 WP_275470166.1 hypothetical protein -
OL235_RS10875 (OL235_10875) 29509..29919 + 411 WP_275470167.1 phage holin family protein -
OL235_RS10880 (OL235_10880) 29952..30737 + 786 WP_275470320.1 N-acetylmuramoyl-L-alanine amidase -
OL235_RS10885 (OL235_10885) 30893..31114 + 222 WP_275470170.1 DUF6290 family protein Antitoxin
OL235_RS10890 (OL235_10890) 31111..31386 + 276 WP_275470171.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OL235_RS10895 (OL235_10895) 31752..32051 + 300 WP_275470321.1 hypothetical protein -
OL235_RS10900 (OL235_10900) 32517..33101 - 585 WP_275470173.1 helix-turn-helix transcriptional regulator -
OL235_RS10905 (OL235_10905) 33629..33829 + 201 WP_275470174.1 cold-shock protein -
OL235_RS10910 (OL235_10910) 33887..34102 + 216 WP_275470175.1 hypothetical protein -
OL235_RS10915 (OL235_10915) 34202..34633 - 432 WP_275470176.1 helix-turn-helix transcriptional regulator -
OL235_RS10920 (OL235_10920) 34949..35302 + 354 WP_275470177.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..42431 42431


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-90)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10672.42 Da        Isoelectric Point: 10.3331

>T263476 WP_275470171.1 NZ_CP110241:31111-31386 [Vagococcus sp. STAA25]
MIEKKYTVRYEKNAQKALKKMDKHQAMLILSWISKNLEGTDSPRVHGKGLVGNKSGQWRYRIGDYRLLANIDDETITILV
LEIGHRREIYK

Download         Length: 276 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8333.39 Da        Isoelectric Point: 4.2690

>AT263476 WP_275470170.1 NZ_CP110241:30893-31114 [Vagococcus sp. STAA25]
MSTVTFRVTDEEKSFIQSMADLNGQTLSELARTKLLEGLEDQIDMGLYEKAMKAHEEKDESISHQDMLRELGL

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References