Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafQ-relB/YafQ-DinJ
Location 2110..2687 Replicon plasmid unnamed2
Accession NZ_CP110239
Organism Vagococcus sp. STAA25

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag OL235_RS10535 Protein ID WP_275470319.1
Coordinates 2394..2687 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OL235_RS10530 Protein ID WP_275470318.1
Coordinates 2110..2385 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OL235_RS10510 (OL235_10510) 28..315 - 288 WP_275470244.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
OL235_RS10515 (OL235_10515) 945..1334 + 390 WP_275470243.1 hypothetical protein -
OL235_RS10520 (OL235_10520) 1358..1570 + 213 WP_275470242.1 hypothetical protein -
OL235_RS10525 (OL235_10525) 1717..1932 + 216 WP_275470241.1 hypothetical protein -
OL235_RS10530 (OL235_10530) 2110..2385 + 276 WP_275470318.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OL235_RS10535 (OL235_10535) 2394..2687 + 294 WP_275470319.1 type II toxin-antitoxin system YafQ family toxin Toxin
OL235_RS10540 (OL235_10540) 3007..3300 + 294 WP_275470239.1 bacteriocin immunity protein -
OL235_RS10545 (OL235_10545) 3595..4020 - 426 WP_275470250.1 cupin domain-containing protein -
OL235_RS10550 (OL235_10550) 4418..4669 + 252 WP_275470238.1 hypothetical protein -
OL235_RS10555 (OL235_10555) 5556..5894 - 339 WP_275470237.1 winged helix-turn-helix transcriptional regulator -
OL235_RS10560 (OL235_10560) 6155..7264 + 1110 WP_275470236.1 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..16539 16539


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-89)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11557.34 Da        Isoelectric Point: 7.3987

>T263474 WP_275470319.1 NZ_CP110239:2394-2687 [Vagococcus sp. STAA25]
MLKLRKTSLFKKQYKKMISSGQYKEEDFVEVLKKLVNQEPLDEKYNDHSLVGQKRPVRELHINPDWLLIYLIDDEELILT
VVQTGNHSDLFGHKQQF

Download         Length: 294 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10290.62 Da        Isoelectric Point: 4.8146

>AT263474 WP_275470318.1 NZ_CP110239:2110-2385 [Vagococcus sp. STAA25]
MTTKNVQIRMENELKEKSDELFNNLGTSTNEAIKIFLSTAVRANGFPFAITLDKPNTKTKKAIEEAYAIQDGKIEAQVYD
TVDNFMNDLRS

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References