Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 32368..32861 Replicon plasmid unnamed1
Accession NZ_CP110233
Organism Vagococcus sp. STAA11

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OL234_RS10725 Protein ID WP_275470171.1
Coordinates 32586..32861 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OL234_RS10720 Protein ID WP_275470170.1
Coordinates 32368..32589 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OL234_RS10695 (OL234_10695) 30492..30698 + 207 WP_275470165.1 hypothetical protein -
OL234_RS10700 (OL234_10700) 30698..30952 + 255 WP_275470166.1 hypothetical protein -
OL234_RS10705 (OL234_10705) 30983..31393 + 411 WP_275470167.1 phage holin family protein -
OL234_RS10710 (OL234_10710) 31426..31662 + 237 WP_275470168.1 hypothetical protein -
OL234_RS10715 (OL234_10715) 31616..32212 + 597 WP_275470169.1 N-acetylmuramoyl-L-alanine amidase -
OL234_RS10720 (OL234_10720) 32368..32589 + 222 WP_275470170.1 DUF6290 family protein Antitoxin
OL234_RS10725 (OL234_10725) 32586..32861 + 276 WP_275470171.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OL234_RS10730 (OL234_10730) 33227..33526 + 300 WP_275470172.1 hypothetical protein -
OL234_RS10735 (OL234_10735) 33992..34576 - 585 WP_275470173.1 helix-turn-helix transcriptional regulator -
OL234_RS10740 (OL234_10740) 35104..35304 + 201 WP_275470174.1 cold-shock protein -
OL234_RS10745 (OL234_10745) 35362..35577 + 216 WP_275470175.1 hypothetical protein -
OL234_RS10750 (OL234_10750) 35677..36108 - 432 WP_275470176.1 helix-turn-helix transcriptional regulator -
OL234_RS10755 (OL234_10755) 36424..36777 + 354 WP_275470177.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..42431 42431


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-90)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10672.42 Da        Isoelectric Point: 10.3331

>T263472 WP_275470171.1 NZ_CP110233:32586-32861 [Vagococcus sp. STAA11]
MIEKKYTVRYEKNAQKALKKMDKHQAMLILSWISKNLEGTDSPRVHGKGLVGNKSGQWRYRIGDYRLLANIDDETITILV
LEIGHRREIYK

Download         Length: 276 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8333.39 Da        Isoelectric Point: 4.2690

>AT263472 WP_275470170.1 NZ_CP110233:32368-32589 [Vagococcus sp. STAA11]
MSTVTFRVTDEEKSFIQSMADLNGQTLSELARTKLLEGLEDQIDMGLYEKAMKAHEEKDESISHQDMLRELGL

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References