Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 2360520..2361058 Replicon chromosome
Accession NZ_CP110231
Organism Selenomonas sputigena strain KCOM 20461

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OL240_RS10790 Protein ID WP_264918409.1
Coordinates 2360520..2360795 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID F4EYL4
Locus tag OL240_RS10795 Protein ID WP_013740585.1
Coordinates 2360792..2361058 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OL240_RS10775 (OL240_10775) 2355903..2357972 + 2070 WP_264918405.1 sulfatase-like hydrolase/transferase -
OL240_RS10780 (OL240_10780) 2358051..2358899 + 849 WP_264918406.1 glycosyltransferase -
OL240_RS10785 (OL240_10785) 2358961..2360385 + 1425 WP_264918408.1 [FeFe] hydrogenase H-cluster radical SAM maturase HydG -
OL240_RS10790 (OL240_10790) 2360520..2360795 - 276 WP_264918409.1 type II toxin-antitoxin system YafQ family toxin Toxin
OL240_RS10795 (OL240_10795) 2360792..2361058 - 267 WP_013740585.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OL240_RS10800 (OL240_10800) 2361396..2361659 + 264 WP_264918410.1 helix-turn-helix transcriptional regulator -
OL240_RS10805 (OL240_10805) 2361874..2362068 + 195 WP_264918411.1 sulfur carrier protein ThiS -
OL240_RS10810 (OL240_10810) 2362162..2362959 + 798 WP_264918412.1 thiazole synthase -
OL240_RS10815 (OL240_10815) 2362956..2364212 + 1257 WP_264918414.1 2-iminoacetate synthase ThiH -
OL240_RS10820 (OL240_10820) 2364205..2364795 + 591 WP_264918416.1 thiamine phosphate synthase -
OL240_RS10825 (OL240_10825) 2364941..2365969 - 1029 WP_264918418.1 nuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-75)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10485.23 Da        Isoelectric Point: 9.1381

>T263470 WP_264918409.1 NZ_CP110231:c2360795-2360520 [Selenomonas sputigena]
MKYKIIPTARFRKDVKTAAKRGLPICRLEEIVDQLAAGTPLPERNRDHALTGTFAGYRECHILPDWLLVYRIDNEILTLL
LHRTGTHSDLF

Download         Length: 276 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9847.36 Da        Isoelectric Point: 5.0508

>AT263470 WP_013740585.1 NZ_CP110231:c2361058-2360792 [Selenomonas sputigena]
MPSTMIRVRMDSALKAQTDAALASMGLNMSVAVNAMARQILRQGRLPFELYATNPETMAALQEAEEIRRNPENFKSYASA
HEMMEDIL

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB F4EYL4

References