Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2199228..2199712 Replicon chromosome
Accession NZ_CP110231
Organism Selenomonas sputigena strain KCOM 20461

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OL240_RS09995 Protein ID WP_264918213.1
Coordinates 2199228..2199494 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID F4EX28
Locus tag OL240_RS10000 Protein ID WP_013741006.1
Coordinates 2199491..2199712 (-) Length 74 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OL240_RS09970 (OL240_09970) 2194471..2195031 - 561 WP_264918206.1 hypothetical protein -
OL240_RS09975 (OL240_09975) 2195457..2195837 - 381 WP_232362398.1 metalloregulator ArsR/SmtB family transcription factor -
OL240_RS09980 (OL240_09980) 2195856..2196167 - 312 WP_264918208.1 hypothetical protein -
OL240_RS09985 (OL240_09985) 2196201..2198138 - 1938 WP_264918210.1 fructose-specific PTS transporter subunit EIIC -
OL240_RS09990 (OL240_09990) 2198168..2199076 - 909 WP_264918212.1 1-phosphofructokinase -
OL240_RS09995 (OL240_09995) 2199228..2199494 - 267 WP_264918213.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OL240_RS10000 (OL240_10000) 2199491..2199712 - 222 WP_013741006.1 DUF6290 family protein Antitoxin
OL240_RS10005 (OL240_10005) 2200113..2200664 + 552 WP_264918216.1 hypothetical protein -
OL240_RS10010 (OL240_10010) 2200739..2201623 + 885 WP_264918218.1 Hsp33 family molecular chaperone HslO -
OL240_RS10015 (OL240_10015) 2202052..2204712 + 2661 WP_264918220.1 valine--tRNA ligase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 89 a.a.        Molecular weight: 10525.30 Da        Isoelectric Point: 10.4114

>T263468 WP_264918213.1 NZ_CP110231:c2199494-2199228 [Selenomonas sputigena]
MKSYRLIYSERAKKDVKKLDPYTKQMIKSWIEKRLLHSENPRAHGKALTGNHKGEWRYRIGDYRLICAIEDERLVILALA
LGHRREVY

Download         Length: 267 bp


Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8483.39 Da        Isoelectric Point: 4.0649

>AT263468 WP_013741006.1 NZ_CP110231:c2199712-2199491 [Selenomonas sputigena]
MSFSIRLTDTERALAESYAKLHALSLAEAFKRALFEKIEDEYDIALADEAYEEYLANPTTYSHEEFWNDVMTP

Download         Length: 222 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB F4EX28

References