Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3928674..3929209 Replicon chromosome
Accession NZ_CP110227
Organism Serratia rubidaea strain AO4-P6

Toxin (Protein)


Gene name relE Uniprot ID A0A4V6JGT0
Locus tag OLD77_RS18760 Protein ID WP_054305341.1
Coordinates 3928922..3929209 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OLD77_RS18755 Protein ID WP_269873428.1
Coordinates 3928674..3928925 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLD77_RS18730 (OLD77_18730) 3924695..3925237 - 543 WP_015671079.1 hypothetical protein -
OLD77_RS18735 (OLD77_18735) 3925237..3925923 - 687 WP_061324887.1 acireductone synthase -
OLD77_RS18740 (OLD77_18740) 3925920..3926534 - 615 WP_269873425.1 methylthioribulose 1-phosphate dehydratase -
OLD77_RS18745 (OLD77_18745) 3926669..3927829 + 1161 WP_015671076.1 pyridoxal phosphate-dependent aminotransferase -
OLD77_RS18750 (OLD77_18750) 3927817..3928590 + 774 WP_061324890.1 amidohydrolase -
OLD77_RS18755 (OLD77_18755) 3928674..3928925 + 252 WP_269873428.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OLD77_RS18760 (OLD77_18760) 3928922..3929209 + 288 WP_054305341.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OLD77_RS18765 (OLD77_18765) 3929525..3930403 - 879 WP_269873431.1 siderophore-interacting protein -
OLD77_RS18770 (OLD77_18770) 3930425..3931627 - 1203 WP_269873433.1 MFS transporter -
OLD77_RS18775 (OLD77_18775) 3931766..3933511 + 1746 WP_269873435.1 IucA/IucC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10946.02 Da        Isoelectric Point: 10.4726

>T263466 WP_054305341.1 NZ_CP110227:3928922-3929209 [Serratia rubidaea]
MTYKVKFRESALKEWNRLDKALQQQFAKKLKKCCENPHIPAAKLRGMPGCYKIKLRASGFRLVYEVIDDCLVIAVVAVGK
RERGSVYQLSSERLK

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9262.54 Da        Isoelectric Point: 4.1079

>AT263466 WP_269873428.1 NZ_CP110227:3928674-3928925 [Serratia rubidaea]
VPNIILSDTSASISELKKNPMGTVNAGEGYPVAILNRNQPAFYCVPAALYERMLDVLDEQELIRLVNERRNEALIDVDLD
QFA

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4V6JGT0

Antitoxin

Source ID Structure

References