Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 978187..978853 Replicon chromosome
Accession NZ_CP110227
Organism Serratia rubidaea strain AO4-P6

Toxin (Protein)


Gene name cptA Uniprot ID A0A4V6JI41
Locus tag OLD77_RS04580 Protein ID WP_054306177.1
Coordinates 978434..978853 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag OLD77_RS04575 Protein ID WP_061322415.1
Coordinates 978187..978453 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLD77_RS04550 (OLD77_04550) 973316..973969 + 654 WP_269874922.1 hypothetical protein -
OLD77_RS04555 (OLD77_04555) 973966..975285 + 1320 WP_015673672.1 MFS transporter -
OLD77_RS04560 (OLD77_04560) 975317..975925 - 609 WP_061322413.1 HD domain-containing protein -
OLD77_RS04565 (OLD77_04565) 976120..976800 + 681 WP_015673670.1 hemolysin III family protein -
OLD77_RS04570 (OLD77_04570) 976855..977847 - 993 WP_015673669.1 tRNA-modifying protein YgfZ -
OLD77_RS04575 (OLD77_04575) 978187..978453 + 267 WP_061322415.1 FAD assembly factor SdhE Antitoxin
OLD77_RS04580 (OLD77_04580) 978434..978853 + 420 WP_054306177.1 protein YgfX Toxin
OLD77_RS04585 (OLD77_04585) 978885..979403 - 519 WP_041411867.1 flavodoxin FldB -
OLD77_RS04590 (OLD77_04590) 979495..980394 + 900 WP_269874925.1 site-specific tyrosine recombinase XerD -
OLD77_RS04595 (OLD77_04595) 980422..981138 + 717 WP_015673664.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OLD77_RS04600 (OLD77_04600) 981151..982881 + 1731 WP_269876071.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16292.19 Da        Isoelectric Point: 11.2220

>T263458 WP_054306177.1 NZ_CP110227:978434-978853 [Serratia rubidaea]
VAQWRCDVRISWRTQLVSLLAHGALILLILISPWPESYDPIWLLLLTLVVFECIRSQTRIASRQGELRLLSAPQRVIWQG
KEWRLARRPWMLRGGMLLTLQASGKRKRRRLWLASDCISSAEWRQLCQRMQLAEDESEG

Download         Length: 420 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10375.82 Da        Isoelectric Point: 5.0843

>AT263458 WP_061322415.1 NZ_CP110227:978187-978453 [Serratia rubidaea]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEDKALFVRLLQSDDPDLFNWLMNHGAPQDAELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4V6JI41

Antitoxin

Source ID Structure

References