Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1112703..1113340 Replicon chromosome
Accession NZ_CP110225
Organism Gallibacterium anatis strain IMT49310

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OLL86_RS05145 Protein ID WP_264780459.1
Coordinates 1112703..1113110 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OLL86_RS05150 Protein ID WP_179255206.1
Coordinates 1113110..1113340 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLL86_RS05130 (OLL86_05130) 1108153..1109271 - 1119 WP_264780457.1 iron-sulfur cluster carrier protein ApbC -
OLL86_RS05135 (OLL86_05135) 1109469..1111514 + 2046 WP_264780511.1 methionine--tRNA ligase -
OLL86_RS05140 (OLL86_05140) 1111599..1112603 + 1005 WP_264780458.1 16S rRNA (guanine(1207)-N(2))-methyltransferase RsmC -
OLL86_RS05145 (OLL86_05145) 1112703..1113110 - 408 WP_264780459.1 tRNA(fMet)-specific endonuclease VapC Toxin
OLL86_RS05150 (OLL86_05150) 1113110..1113340 - 231 WP_179255206.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
OLL86_RS05155 (OLL86_05155) 1113640..1114635 + 996 WP_264780460.1 thiamine ABC transporter substrate binding subunit -
OLL86_RS05160 (OLL86_05160) 1114611..1116233 + 1623 WP_264780461.1 thiamine/thiamine pyrophosphate ABC transporter permease -
OLL86_RS05165 (OLL86_05165) 1116220..1116882 + 663 WP_264780462.1 thiamine ABC transporter ATP-binding protein -
OLL86_RS05170 (OLL86_05170) 1116922..1117932 + 1011 WP_264780463.1 biotin synthase BioB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15032.60 Da        Isoelectric Point: 7.2411

>T263455 WP_264780459.1 NZ_CP110225:c1113110-1112703 [Gallibacterium anatis]
MLKYMLDTNIVIFTIKNKPPHLLPLFNENQSMLCISSITLMELVYGAEKSKKMAQNLAVIESFCARLAVLDYDEAAAYHS
GQIRAELAKIGQPIGPYDAMIAGHARSLGLTVVTNNMNDFSRVEGLRVIDWSKPM

Download         Length: 408 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8725.84 Da        Isoelectric Point: 4.4013

>AT263455 WP_179255206.1 NZ_CP110225:c1113340-1113110 [Gallibacterium anatis]
VTATVFMNNKSQAIRIPKAAELPNTTKSVNIIIQGDMRIITPLNNVWDSWFNDSNSVSDDFMLSREQPQMQEREEL

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References