Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1063294..1063839 Replicon chromosome
Accession NZ_CP110225
Organism Gallibacterium anatis strain IMT49310

Toxin (Protein)


Gene name relE Uniprot ID F4HF99
Locus tag OLL86_RS04920 Protein ID WP_013746939.1
Coordinates 1063294..1063581 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0A2ZZB6
Locus tag OLL86_RS04925 Protein ID WP_039087491.1
Coordinates 1063591..1063839 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLL86_RS04890 (OLL86_04890) 1058568..1059494 + 927 WP_039083772.1 phosphoserine phosphatase -
OLL86_RS04895 (OLL86_04895) 1059507..1059998 + 492 WP_013746944.1 YajQ family cyclic di-GMP-binding protein -
OLL86_RS04900 (OLL86_04900) 1060020..1060187 + 168 WP_018345760.1 DUF5363 family protein -
OLL86_RS04905 (OLL86_04905) 1060272..1062287 + 2016 WP_264780428.1 NAD-dependent DNA ligase LigA -
OLL86_RS04910 (OLL86_04910) 1062491..1062757 + 267 WP_018345762.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
OLL86_RS04915 (OLL86_04915) 1062757..1063110 + 354 WP_264780429.1 type II toxin-antitoxin system PemK/MazF family toxin -
OLL86_RS04920 (OLL86_04920) 1063294..1063581 - 288 WP_013746939.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OLL86_RS04925 (OLL86_04925) 1063591..1063839 - 249 WP_039087491.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OLL86_RS04930 (OLL86_04930) 1063956..1065008 - 1053 WP_039092160.1 porin -
OLL86_RS04935 (OLL86_04935) 1065363..1065734 + 372 WP_264780430.1 hypothetical protein -
OLL86_RS04940 (OLL86_04940) 1066392..1067474 - 1083 WP_264780431.1 porin -
OLL86_RS04945 (OLL86_04945) 1067730..1068653 - 924 WP_264780432.1 tRNA pseudouridine(55) synthase TruB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-73)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11026.94 Da        Isoelectric Point: 10.4262

>T263454 WP_013746939.1 NZ_CP110225:c1063581-1063294 [Gallibacterium anatis]
MAYAIKVHSDFVAELNKLDSTIKNQLRKKLEKVVHNPHIPKNRLSGELHNCYKIKLRKAGVRLVYQVNDDEIYILLLTVG
KREAKQVYNTALNRV

Download         Length: 288 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9345.69 Da        Isoelectric Point: 4.4230

>AT263454 WP_039087491.1 NZ_CP110225:c1063839-1063591 [Gallibacterium anatis]
MANLNIRIDDTIKQRAFLAFDNLGINPSEAIRTFLTYVADTGRMPIKQIIVSDEDAELYEVVKKRLNEPEKITATTLDEL
FS

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB F4HF99

Antitoxin

Source ID Structure
AlphaFold DB A0A0A2ZZB6

References