26345

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 10359..10851 Replicon plasmid pZMOB01
Accession NC_017180
Organism Zymomonas mobilis subsp. mobilis ATCC 10988

Toxin (Protein)


Gene name pasB Uniprot ID A0A0H3G3Z2
Locus tag ZMOB_RS09120 Protein ID WP_014466394.1
Coordinates 10567..10851 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID A0A0H3G0Q6
Locus tag ZMOB_RS09115 Protein ID WP_014466393.1
Coordinates 10359..10583 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ZMOB_RS09105 5710..6813 - 1104 WP_014466391.1 histidinol-phosphate aminotransferase family protein -
ZMOB_RS09110 7009..9597 + 2589 WP_148235956.1 TonB-dependent receptor -
ZMOB_RS09115 10359..10583 + 225 WP_014466393.1 TraY domain-containing protein Antitoxin
ZMOB_RS09120 10567..10851 + 285 WP_014466394.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ZMOB_RS09125 10954..11586 + 633 WP_014466395.1 ParA family protein -
ZMOB_RS09130 11583..11858 + 276 WP_014466396.1 hypothetical protein -
ZMOB_RS09140 13115..14713 + 1599 WP_014466397.1 AAA family ATPase -
ZMOB_RS09980 15455..15727 - 273 WP_014466399.1 type II toxin-antitoxin system YafQ family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..32479 32479


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Relaxosome protein TraY

(4-49)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10835.85 Da        Isoelectric Point: 11.0388

>T26345 WP_014466394.1 NC_017180:10567-10851 [Zymomonas mobilis subsp. mobilis ATCC 10988]
MAWKIEFDPAAQKELKKLGTQPAKRILKFLSERLASTDNPRSLGAALKGSALGSLWKYRIGDYRVIVDIEDKMLRILVVR
IGNRREIYKKVVRH

Download         Length: 285 bp

>T26345 NC_017180:10567-10851 [Zymomonas mobilis subsp. mobilis ATCC 10988]
ATGGCTTGGAAAATTGAGTTCGATCCAGCCGCTCAAAAAGAGTTAAAAAAATTAGGAACGCAGCCAGCTAAGCGCATCTT
AAAATTTTTATCCGAACGTTTGGCTTCAACCGATAATCCAAGATCATTAGGTGCTGCTTTAAAGGGGAGCGCTCTAGGCA
GCTTATGGAAATATAGGATTGGTGATTATCGCGTCATTGTCGATATTGAAGATAAGATGCTGCGTATTTTGGTTGTCAGA
ATTGGCAACAGAAGAGAAATCTATAAAAAAGTTGTGCGGCACTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8438.66 Da        Isoelectric Point: 5.1442

>AT26345 WP_014466393.1 NC_017180:10359-10583 [Zymomonas mobilis subsp. mobilis ATCC 10988]
MLAIRLPEEIEDRLSQLAKATGRTKTFYAREAILQHLEELEDTYLAEARAIKIRSGKTKTVSLENVMAEYGLEN

Download         Length: 225 bp

>AT26345 NC_017180:10359-10583 [Zymomonas mobilis subsp. mobilis ATCC 10988]
ATGTTGGCAATTCGTTTACCAGAAGAAATTGAAGATCGTCTCAGCCAGCTAGCGAAGGCGACCGGCCGGACCAAAACCTT
TTATGCCAGAGAAGCTATACTTCAACATTTGGAAGAGCTGGAAGATACTTATCTTGCAGAGGCGCGTGCCATCAAAATTC
GTTCAGGGAAGACTAAAACTGTTTCTTTAGAAAATGTCATGGCTGAATATGGCTTGGAAAATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3G3Z2

Antitoxin

Source ID Structure
AlphaFold DB A0A0H3G0Q6

References