Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907(toxin)
Location 1775594..1776042 Replicon chromosome
Accession NZ_CP110217
Organism Lactobacillus sp. IBH004

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag LDX54_RS08810 Protein ID WP_265667387.1
Coordinates 1775710..1776042 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag LDX54_RS08805 Protein ID WP_265667389.1
Coordinates 1775594..1775716 (+) Length 41 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDX54_RS08790 (LDX54_02640) 1771420..1772763 - 1344 WP_265667392.1 6-phospho-alpha-glucosidase -
LDX54_RS08795 (LDX54_02635) 1772998..1773927 - 930 WP_265667391.1 cytochrome C5 -
LDX54_RS08800 (LDX54_02630) 1774079..1775317 + 1239 WP_265667390.1 MFS transporter -
LDX54_RS08805 (LDX54_02625) 1775594..1775716 + 123 WP_265667389.1 hypothetical protein Antitoxin
LDX54_RS08810 (LDX54_02620) 1775710..1776042 + 333 WP_265667387.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
LDX54_RS08815 (LDX54_02615) 1776616..1777860 - 1245 WP_265667386.1 MFS transporter -
LDX54_RS08820 (LDX54_02610) 1777966..1778823 + 858 WP_265667385.1 hypothetical protein -
LDX54_RS08825 (LDX54_02605) 1779025..1779660 + 636 WP_265667384.1 hypothetical protein -
LDX54_RS08830 (LDX54_02600) 1780174..1780641 - 468 WP_265667383.1 PBECR4 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-107)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 12665.80 Da        Isoelectric Point: 9.6357

>T263431 WP_265667387.1 NZ_CP110217:1775710-1776042 [Lactobacillus sp. IBH004]
MVIKQGSILLMDLSPKQGHEQSGKRPYLYLSYKGVEKYAHIAVFAPIATTKRRYPLYQELPAASQTKGVVMLDQLVTIDY
HNQSFQYLEQLPDDYMGKILKIVKVVFQKD

Download         Length: 333 bp

Antitoxin


Download         Length: 41 a.a.        Molecular weight: 4812.21 Da        Isoelectric Point: 3.9798

>AT263431 WP_265667389.1 NZ_CP110217:1775594-1775716 [Lactobacillus sp. IBH004]
MSKQDDTPDLTFEELFKDYSGEEFDTEIKLPDERKGNEKW

Download         Length: 123 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References