Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-RelB |
Location | 4207373..4207889 | Replicon | chromosome |
Accession | NZ_CP110201 | ||
Organism | Salmonella enterica subsp. enterica serovar Typhimurium strain 1104-65 |
Toxin (Protein)
Gene name | relE | Uniprot ID | C0Q7A9 |
Locus tag | OCK73_RS20485 | Protein ID | WP_000220578.1 |
Coordinates | 4207373..4207657 (-) | Length | 95 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | V7ISI8 |
Locus tag | OCK73_RS20490 | Protein ID | WP_000212724.1 |
Coordinates | 4207647..4207889 (-) | Length | 81 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OCK73_RS20470 (4202585) | 4202585..4204237 | + | 1653 | WP_000155057.1 | alpha,alpha-phosphotrehalase | - |
OCK73_RS20475 (4204646) | 4204646..4206784 | + | 2139 | WP_000187818.1 | anaerobic ribonucleoside-triphosphate reductase | - |
OCK73_RS20480 (4206905) | 4206905..4207369 | + | 465 | WP_001268859.1 | anaerobic ribonucleoside-triphosphate reductase-activating protein | - |
OCK73_RS20485 (4207373) | 4207373..4207657 | - | 285 | WP_000220578.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
OCK73_RS20490 (4207647) | 4207647..4207889 | - | 243 | WP_000212724.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
OCK73_RS20495 (4207967) | 4207967..4209880 | - | 1914 | WP_001212137.1 | BglG family transcription antiterminator | - |
OCK73_RS20500 (4209897) | 4209897..4210637 | - | 741 | WP_000779263.1 | KDGP aldolase family protein | - |
OCK73_RS20505 (4210634) | 4210634..4211752 | - | 1119 | WP_001139182.1 | DgaE family pyridoxal phosphate-dependent ammonia lyase | - |
OCK73_RS20510 (4211736) | 4211736..4212869 | - | 1134 | WP_000459930.1 | amidohydrolase/deacetylase family metallohydrolase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 95 a.a. Molecular weight: 10854.67 Da Isoelectric Point: 10.0482
>T263425 WP_000220578.1 NZ_CP110201:c4207657-4207373 [Salmonella enterica subsp. enterica serovar Typhimurium]
MTYELEFDPRALKEWHKLGDTVKAQLKKKLADVLLNPRIDSARLNGLPDCYKIKLKSSGYRLVYQVRDDVVIVFVVAVGK
REHSAVYHDANKRL
MTYELEFDPRALKEWHKLGDTVKAQLKKKLADVLLNPRIDSARLNGLPDCYKIKLKSSGYRLVYQVRDDVVIVFVVAVGK
REHSAVYHDANKRL
Download Length: 285 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3Z1E876 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A5H5JRI5 |