Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1938334..1938479 Replicon chromosome
Accession NZ_CP110193
Organism Klebsiella pneumoniae strain FK563

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1938370..1938472 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1938334..1938479 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OEW01_RS09310 1933464..1935524 + 2061 WP_004151449.1 oligopeptidase B -
OEW01_RS09315 1935528..1936187 - 660 WP_002911407.1 exodeoxyribonuclease X -
OEW01_RS09320 1936266..1936496 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OEW01_RS09325 1936609..1936983 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OEW01_RS09330 1936987..1937856 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
OEW01_RS09335 1937873..1938211 + 339 WP_002911404.1 YebY family protein -
- 1938334..1938479 - 146 - - Antitoxin
- 1938370..1938472 + 103 - - Toxin
OEW01_RS09340 1938847..1938990 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OEW01_RS09345 1939095..1940063 - 969 WP_004151446.1 VirK/YbjX family protein -
OEW01_RS09350 1940220..1940873 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
OEW01_RS09355 1940870..1941061 - 192 WP_002911395.1 YebW family protein -
OEW01_RS09360 1941159..1941398 - 240 WP_002911393.1 YebV family protein -
OEW01_RS09365 1941514..1942947 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T263368 NZ_CP110193:1938370-1938472 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT263368 NZ_CP110193:c1938479-1938334 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References