Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 4562670..4563928 Replicon chromosome
Accession NZ_CP110190
Organism Pseudomonas aeruginosa strain HS204

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag OMP51_RS21415 Protein ID WP_028681273.1
Coordinates 4562670..4563425 (-) Length 252 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag OMP51_RS21420 Protein ID WP_028681272.1
Coordinates 4563560..4563928 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OMP51_RS21405 (OMP51_21390) 4557841..4560384 + 2544 WP_028681274.1 acyl-homoserine-lactone acylase QuiP -
OMP51_RS21410 (OMP51_21395) 4560539..4561900 - 1362 WP_003081943.1 DNA recombination protein RmuC -
OMP51_RS21415 (OMP51_21400) 4562670..4563425 - 756 WP_028681273.1 RES family NAD+ phosphorylase Toxin
OMP51_RS21420 (OMP51_21405) 4563560..4563928 - 369 WP_028681272.1 DUF2384 domain-containing protein Antitoxin
OMP51_RS21425 (OMP51_21410) 4564001..4565287 - 1287 WP_003163134.1 FAD-binding oxidoreductase -
OMP51_RS21430 (OMP51_21415) 4565343..4566836 - 1494 WP_003086325.1 aldehyde dehydrogenase family protein -
OMP51_RS21435 (OMP51_21420) 4567011..4567487 + 477 WP_003112531.1 hypothetical protein -
OMP51_RS21440 (OMP51_21425) 4567490..4567765 - 276 WP_010792073.1 zinc ribbon domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(63-207)

Antitoxin

Cro/C1-type helix-turn-helix domain

(23-47)


Sequences

Toxin        


Download         Length: 252 a.a.        Molecular weight: 28262.43 Da        Isoelectric Point: 7.7294

>T263357 WP_028681273.1 NZ_CP110190:c4563425-4562670 [Pseudomonas aeruginosa]
VSEIWRQCKGERHIRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMVVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGAPKIFSWEL
FLVDGKLPHPA

Download         Length: 756 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13395.68 Da        Isoelectric Point: 10.2722

>AT263357 WP_028681272.1 NZ_CP110190:c4563928-4563560 [Pseudomonas aeruginosa]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGRVQGLVHVLEYLDAIRGKV

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References