Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-YafN |
| Location | 1053440..1053968 | Replicon | chromosome |
| Accession | NZ_CP110189 | ||
| Organism | Vibrio cholerae strain E1 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A0X1KZS6 |
| Locus tag | OFY13_RS18335 | Protein ID | WP_000221354.1 |
| Coordinates | 1053440..1053727 (-) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A0X1KZS8 |
| Locus tag | OFY13_RS18340 | Protein ID | WP_001250179.1 |
| Coordinates | 1053717..1053968 (-) | Length | 84 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OFY13_RS18290 (OFY13_18290) | 1048938..1049000 | - | 63 | Protein_938 | DUF645 family protein | - |
| OFY13_RS18295 (OFY13_18295) | 1049362..1049757 | - | 396 | WP_000870864.1 | DUF3465 domain-containing protein | - |
| OFY13_RS18300 (OFY13_18300) | 1049973..1050126 | - | 154 | Protein_940 | DUF645 family protein | - |
| OFY13_RS18305 (OFY13_18305) | 1050187..1050363 | - | 177 | WP_080003854.1 | acetyltransferase | - |
| OFY13_RS18310 (OFY13_18310) | 1050479..1050660 | - | 182 | Protein_942 | DUF645 family protein | - |
| OFY13_RS18315 (OFY13_18315) | 1051013..1051192 | - | 180 | WP_025998961.1 | DUF645 family protein | - |
| OFY13_RS18320 (OFY13_18320) | 1051489..1052070 | - | 582 | WP_043990376.1 | nucleotidyltransferase family protein | - |
| OFY13_RS18325 (OFY13_18325) | 1052220..1052324 | - | 105 | WP_228840819.1 | DUF645 family protein | - |
| OFY13_RS18330 (OFY13_18330) | 1052695..1053294 | - | 600 | WP_057558148.1 | glutathione S-transferase N-terminal domain-containing protein | - |
| OFY13_RS18335 (OFY13_18335) | 1053440..1053727 | - | 288 | WP_000221354.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| OFY13_RS18340 (OFY13_18340) | 1053717..1053968 | - | 252 | WP_001250179.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| OFY13_RS18345 (OFY13_18345) | 1054172..1054711 | - | 540 | WP_001898634.1 | histidine phosphatase family protein | - |
| OFY13_RS18350 (OFY13_18350) | 1054864..1055361 | - | 498 | WP_000259905.1 | GNAT family N-acetyltransferase | - |
| OFY13_RS18355 (OFY13_18355) | 1055537..1055794 | - | 258 | WP_001893682.1 | hypothetical protein | - |
| OFY13_RS18360 (OFY13_18360) | 1055878..1055988 | - | 111 | WP_080003855.1 | DUF3265 domain-containing protein | - |
| OFY13_RS18365 (OFY13_18365) | 1055991..1056632 | - | 642 | WP_000582578.1 | hypothetical protein | - |
| OFY13_RS18370 (OFY13_18370) | 1056769..1057257 | - | 489 | WP_000424242.1 | hypothetical protein | - |
| OFY13_RS18375 (OFY13_18375) | 1057507..1057728 | - | 222 | WP_041163199.1 | DUF1289 domain-containing protein | - |
| OFY13_RS18380 (OFY13_18380) | 1057748..1057909 | - | 162 | WP_080385993.1 | DUF3265 domain-containing protein | - |
| OFY13_RS18385 (OFY13_18385) | 1058332..1058727 | - | 396 | WP_001000868.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integron | - | hlyA / vgrG-3 / vasL / icmF/vasK / vasJ / vasI / vasH / clpB/vasG / vasF / vasE / vasD / vasC / vasB / vasA / VCA0109 / vipB/mglB / vipA/mglA / vgrG-2 / hcp-2 / hlyA / htpB / ugd / cqsA | 44..1062811 | 1062767 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0X1KZS6 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0X1KZS8 |