Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-Phd |
| Location | 1036227..1036774 | Replicon | chromosome |
| Accession | NZ_CP110189 | ||
| Organism | Vibrio cholerae strain E1 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | OFY13_RS18175 | Protein ID | WP_131476981.1 |
| Coordinates | 1036227..1036529 (-) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | Q9KM93 |
| Locus tag | OFY13_RS18180 | Protein ID | WP_000861987.1 |
| Coordinates | 1036517..1036774 (-) | Length | 86 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OFY13_RS18125 (OFY13_18125) | 1031251..1031421 | - | 171 | WP_001080654.1 | hypothetical protein | - |
| OFY13_RS18130 (OFY13_18130) | 1031503..1031940 | - | 438 | WP_000503164.1 | IS200/IS605-like element IS1004 family transposase | - |
| OFY13_RS18135 (OFY13_18135) | 1031984..1032247 | - | 264 | Protein_907 | GNAT family N-acetyltransferase | - |
| OFY13_RS18140 (OFY13_18140) | 1032318..1033507 | + | 1190 | WP_088124793.1 | IS3 family transposase | - |
| OFY13_RS18145 (OFY13_18145) | 1033517..1033840 | - | 324 | Protein_909 | GNAT family N-acetyltransferase | - |
| OFY13_RS18150 (OFY13_18150) | 1033977..1034637 | - | 661 | Protein_910 | Vat family streptogramin A O-acetyltransferase | - |
| OFY13_RS18155 (OFY13_18155) | 1034755..1035060 | - | 306 | WP_000063756.1 | hypothetical protein | - |
| OFY13_RS18160 (OFY13_18160) | 1035179..1035526 | - | 348 | WP_000933406.1 | hypothetical protein | - |
| OFY13_RS18165 (OFY13_18165) | 1035734..1035904 | - | 171 | WP_000483444.1 | DUF645 family protein | - |
| OFY13_RS18170 (OFY13_18170) | 1035990..1036148 | - | 159 | Protein_914 | acetyltransferase | - |
| OFY13_RS18175 (OFY13_18175) | 1036227..1036529 | - | 303 | WP_131476981.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| OFY13_RS18180 (OFY13_18180) | 1036517..1036774 | - | 258 | WP_000861987.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| OFY13_RS18185 (OFY13_18185) | 1037025..1037204 | - | 180 | WP_025998961.1 | DUF645 family protein | - |
| OFY13_RS18190 (OFY13_18190) | 1037375..1037443 | - | 69 | Protein_918 | acetyltransferase | - |
| OFY13_RS18195 (OFY13_18195) | 1037499..1037996 | - | 498 | WP_000259905.1 | GNAT family N-acetyltransferase | - |
| OFY13_RS18200 (OFY13_18200) | 1038194..1038619 | - | 426 | WP_000415750.1 | hypothetical protein | - |
| OFY13_RS18205 (OFY13_18205) | 1038904..1039452 | - | 549 | WP_000059064.1 | hypothetical protein | - |
| OFY13_RS18210 (OFY13_18210) | 1039593..1040132 | - | 540 | WP_001898634.1 | histidine phosphatase family protein | - |
| OFY13_RS18215 (OFY13_18215) | 1040164..1040229 | - | 66 | Protein_923 | acetyltransferase | - |
| OFY13_RS18220 (OFY13_18220) | 1040304..1040600 | - | 297 | WP_000617997.1 | Dabb family protein | - |
| OFY13_RS18225 (OFY13_18225) | 1040740..1041285 | - | 546 | WP_000494513.1 | GNAT family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1003220..1033507 | 30287 | |
| - | inside | Integron | - | hlyA / vgrG-3 / vasL / icmF/vasK / vasJ / vasI / vasH / clpB/vasG / vasF / vasE / vasD / vasC / vasB / vasA / VCA0109 / vipB/mglB / vipA/mglA / vgrG-2 / hcp-2 / hlyA / htpB / ugd / cqsA | 44..1062811 | 1062767 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11739.64 Da Isoelectric Point: 4.8838
>T263352 WP_131476981.1 NZ_CP110189:c1036529-1036227 [Vibrio cholerae]
MVEIIWTEPALSDLNDIAEYIALENVVAAKQLVQTVFTKVERLADFPESGRVPPELEHLNYREVVVNLCRVFYKYDDANV
RILFVMRAERDLRRLMLTKQ
MVEIIWTEPALSDLNDIAEYIALENVVAAKQLVQTVFTKVERLADFPESGRVPPELEHLNYREVVVNLCRVFYKYDDANV
RILFVMRAERDLRRLMLTKQ
Download Length: 303 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|