Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1957054..1957199 Replicon chromosome
Accession NZ_CP110170
Organism Klebsiella pneumoniae strain YZ22PK089

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1957090..1957192 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1957054..1957199 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OK017_RS09600 1952184..1954244 + 2061 WP_004151449.1 oligopeptidase B -
OK017_RS09605 1954248..1954907 - 660 WP_021440386.1 exodeoxyribonuclease X -
OK017_RS09610 1954986..1955216 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OK017_RS09615 1955329..1955703 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OK017_RS09620 1955707..1956576 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
OK017_RS09625 1956593..1956931 + 339 WP_002911404.1 YebY family protein -
- 1957054..1957199 - 146 - - Antitoxin
- 1957090..1957192 + 103 - - Toxin
OK017_RS09630 1957568..1957711 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OK017_RS09635 1957816..1958784 - 969 WP_004151446.1 VirK/YbjX family protein -
OK017_RS09640 1958941..1959594 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
OK017_RS09645 1959591..1959782 - 192 WP_002911395.1 YebW family protein -
OK017_RS09650 1959880..1960119 - 240 WP_002911393.1 YebV family protein -
OK017_RS09655 1960235..1961668 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T263333 NZ_CP110170:1957090-1957192 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT263333 NZ_CP110170:c1957199-1957054 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References