Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1872526..1872671 Replicon chromosome
Accession NZ_CP110167
Organism Klebsiella pneumoniae strain YZ22CS094

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1872562..1872664 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1872526..1872671 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OK019_RS09115 1867656..1869716 + 2061 WP_019705169.1 oligopeptidase B -
OK019_RS09120 1869720..1870379 - 660 WP_002911407.1 exodeoxyribonuclease X -
OK019_RS09125 1870458..1870688 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OK019_RS09130 1870801..1871175 + 375 WP_014343244.1 CopC domain-containing protein YobA -
OK019_RS09135 1871179..1872048 + 870 WP_014343243.1 copper homeostasis membrane protein CopD -
OK019_RS09140 1872065..1872403 + 339 WP_002911404.1 YebY family protein -
- 1872526..1872671 - 146 - - Antitoxin
- 1872562..1872664 + 103 - - Toxin
OK019_RS09145 1873039..1873182 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OK019_RS09150 1873287..1874255 - 969 WP_004151446.1 VirK/YbjX family protein -
OK019_RS09155 1874412..1875065 + 654 WP_014343242.1 protein-serine/threonine phosphatase -
OK019_RS09160 1875062..1875253 - 192 WP_002911395.1 YebW family protein -
OK019_RS09165 1875351..1875590 - 240 WP_002911393.1 YebV family protein -
OK019_RS09170 1875706..1877139 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T263316 NZ_CP110167:1872562-1872664 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT263316 NZ_CP110167:c1872671-1872526 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References