Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1916741..1916886 Replicon chromosome
Accession NZ_CP110160
Organism Klebsiella pneumoniae strain YZ22CS089

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1916777..1916879 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1916741..1916886 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OMD38_RS09360 1911871..1913931 + 2061 WP_004151449.1 oligopeptidase B -
OMD38_RS09365 1913935..1914594 - 660 WP_020324964.1 exodeoxyribonuclease X -
OMD38_RS09370 1914673..1914903 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OMD38_RS09375 1915016..1915390 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OMD38_RS09380 1915394..1916263 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
OMD38_RS09385 1916280..1916618 + 339 WP_002911404.1 YebY family protein -
- 1916741..1916886 - 146 - - Antitoxin
- 1916777..1916879 + 103 - - Toxin
OMD38_RS09390 1917255..1917398 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OMD38_RS09395 1917503..1918471 - 969 WP_004151446.1 VirK/YbjX family protein -
OMD38_RS09400 1918628..1919281 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OMD38_RS09405 1919278..1919469 - 192 WP_002911395.1 YebW family protein -
OMD38_RS09410 1919567..1919806 - 240 WP_002911393.1 YebV family protein -
OMD38_RS09415 1919922..1921355 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T263298 NZ_CP110160:1916777-1916879 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT263298 NZ_CP110160:c1916886-1916741 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References