Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1916859..1917004 Replicon chromosome
Accession NZ_CP110153
Organism Klebsiella pneumoniae strain YZ22CS088

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1916895..1916997 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1916859..1917004 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OMD36_RS09355 1911989..1914049 + 2061 WP_004151449.1 oligopeptidase B -
OMD36_RS09360 1914053..1914712 - 660 WP_020324964.1 exodeoxyribonuclease X -
OMD36_RS09365 1914791..1915021 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OMD36_RS09370 1915134..1915508 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OMD36_RS09375 1915512..1916381 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
OMD36_RS09380 1916398..1916736 + 339 WP_002911404.1 YebY family protein -
- 1916859..1917004 - 146 - - Antitoxin
- 1916895..1916997 + 103 - - Toxin
OMD36_RS09385 1917373..1917516 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OMD36_RS09390 1917621..1918589 - 969 WP_004151446.1 VirK/YbjX family protein -
OMD36_RS09395 1918746..1919399 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OMD36_RS09400 1919396..1919587 - 192 WP_002911395.1 YebW family protein -
OMD36_RS09405 1919685..1919924 - 240 WP_002911393.1 YebV family protein -
OMD36_RS09410 1920040..1921473 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T263278 NZ_CP110153:1916895-1916997 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT263278 NZ_CP110153:c1917004-1916859 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References