Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1866717..1866862 Replicon chromosome
Accession NZ_CP110150
Organism Klebsiella pneumoniae strain YZ22CS072

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1866753..1866855 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1866717..1866862 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OK018_RS09050 1861847..1863907 + 2061 WP_048289976.1 oligopeptidase B -
OK018_RS09055 1863911..1864570 - 660 WP_002911407.1 exodeoxyribonuclease X -
OK018_RS09060 1864649..1864879 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OK018_RS09065 1864992..1865366 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OK018_RS09070 1865370..1866239 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
OK018_RS09075 1866256..1866594 + 339 WP_016529031.1 YebY family protein -
- 1866717..1866862 - 146 - - Antitoxin
- 1866753..1866855 + 103 - - Toxin
OK018_RS09080 1867229..1867372 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OK018_RS09085 1867477..1868445 - 969 WP_004151446.1 VirK/YbjX family protein -
OK018_RS09090 1868602..1869255 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
OK018_RS09095 1869252..1869443 - 192 WP_002911395.1 YebW family protein -
OK018_RS09100 1869541..1869780 - 240 WP_002911393.1 YebV family protein -
OK018_RS09105 1869896..1871329 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T263261 NZ_CP110150:1866753-1866855 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT263261 NZ_CP110150:c1866862-1866717 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References