Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 2657966..2658504 Replicon chromosome
Accession NZ_CP110136
Organism Hymenobacter sp. YIM 151858-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OIS50_RS11830 Protein ID WP_264690847.1
Coordinates 2657966..2658283 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OIS50_RS11835 Protein ID WP_264690848.1
Coordinates 2658280..2658504 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OIS50_RS11805 (OIS50_11805) 2653794..2654072 - 279 WP_264690842.1 hypothetical protein -
OIS50_RS11810 (OIS50_11810) 2654047..2655036 - 990 WP_264690843.1 hypothetical protein -
OIS50_RS11815 (OIS50_11815) 2655133..2656497 - 1365 WP_264690844.1 amino acid permease -
OIS50_RS11820 (OIS50_11820) 2656646..2657155 - 510 WP_264690845.1 DUF2480 family protein -
OIS50_RS11825 (OIS50_11825) 2657236..2657931 - 696 WP_264690846.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB -
OIS50_RS11830 (OIS50_11830) 2657966..2658283 - 318 WP_264690847.1 DUF5615 family PIN-like protein Toxin
OIS50_RS11835 (OIS50_11835) 2658280..2658504 - 225 WP_264690848.1 DUF433 domain-containing protein Antitoxin
OIS50_RS11840 (OIS50_11840) 2658765..2660465 - 1701 WP_264690849.1 S41 family peptidase -
OIS50_RS11845 (OIS50_11845) 2660495..2660938 - 444 WP_264690850.1 ribonuclease P protein component -
OIS50_RS11850 (OIS50_11850) 2660985..2661143 - 159 WP_078014902.1 50S ribosomal protein L34 -
OIS50_RS11855 (OIS50_11855) 2661284..2663044 + 1761 WP_264690851.1 PDZ domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-78)

Antitoxin

Protein of unknown function DUF433

(8-63)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11799.75 Da        Isoelectric Point: 7.9865

>T263191 WP_264690847.1 NZ_CP110136:c2658283-2657966 [Hymenobacter sp. YIM 151858-1]
MTLWLDAQLSPLLAVWLRWKFGLNASALRDIGLRDAKDEEIFRAARTANAVVVSKDADFLRLLERYGPPPQIIWITCGNT
ANERLQQVLLATLPAALELLAASRW

Download         Length: 318 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8040.26 Da        Isoelectric Point: 4.8888

>AT263191 WP_264690848.1 NZ_CP110136:c2658504-2658280 [Hymenobacter sp. YIM 151858-1]
MDSLRQRITSDPQQCGGRPCIRGMRIRVADVLNLLAAGLSAEQVLAEMPDLEPLDIQAALQYAAQRLDHPSLAA

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References