Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 5418475..5419010 Replicon chromosome
Accession NZ_CP110131
Organism Methylorubrum extorquens strain NBC_00036

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag OKB92_RS25685 Protein ID WP_265222622.1
Coordinates 5418475..5418765 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag OKB92_RS25690 Protein ID WP_265222623.1
Coordinates 5418762..5419010 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OKB92_RS25655 (OKB92_25655) 5413787..5413987 + 201 WP_003605412.1 hypothetical protein -
OKB92_RS25660 (OKB92_25660) 5414210..5414833 + 624 WP_265222617.1 TetR/AcrR family transcriptional regulator -
OKB92_RS25665 (OKB92_25665) 5414851..5415195 - 345 WP_003605408.1 DUF1330 domain-containing protein -
OKB92_RS25670 (OKB92_25670) 5415198..5415896 - 699 WP_265222618.1 orotidine-5'-phosphate decarboxylase -
OKB92_RS25675 (OKB92_25675) 5416221..5417747 + 1527 WP_265222619.1 alginate export family protein -
OKB92_RS25680 (OKB92_25680) 5417755..5418417 - 663 WP_265222621.1 uracil-DNA glycosylase family protein -
OKB92_RS25685 (OKB92_25685) 5418475..5418765 - 291 WP_265222622.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OKB92_RS25690 (OKB92_25690) 5418762..5419010 - 249 WP_265222623.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
OKB92_RS25695 (OKB92_25695) 5419144..5420646 + 1503 WP_265222624.1 glucose-6-phosphate dehydrogenase -
OKB92_RS25700 (OKB92_25700) 5420842..5422209 + 1368 WP_265222625.1 SWIM zinc finger family protein -
OKB92_RS25705 (OKB92_25705) 5422209..5423792 + 1584 WP_265222626.1 DUF5691 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

Antitoxin ParD

(1-81)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11011.56 Da        Isoelectric Point: 10.5105

>T263190 WP_265222622.1 NZ_CP110131:c5418765-5418475 [Methylorubrum extorquens]
MSVRLSPRARGDLSRIWDDSAERWGADQADRYIRLLAGGFDRLAEDPARGLRADEIRKGYFRLSVGSHVLFYRLGAEGGI
EVIRILHGRMDFKRHL

Download         Length: 291 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9024.95 Da        Isoelectric Point: 4.5292

>AT263190 WP_265222623.1 NZ_CP110131:c5419010-5418762 [Methylorubrum extorquens]
MSRNTSVSLGEHFAQFIDRQVEGGRYGSASEVVRAGLRLLEEQEAALNTLRAALIEGEESGSPEPFDTETFLREKREGAI
RG

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References