Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ParST/RES-Xre
Location 5130884..5131869 Replicon chromosome
Accession NZ_CP110131
Organism Methylorubrum extorquens strain NBC_00036

Toxin (Protein)


Gene name ParT Uniprot ID -
Locus tag OKB92_RS24405 Protein ID WP_265222458.1
Coordinates 5130884..5131381 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name ParS Uniprot ID -
Locus tag OKB92_RS24410 Protein ID WP_056155356.1
Coordinates 5131378..5131869 (-) Length 164 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OKB92_RS24385 (OKB92_24385) 5127028..5127579 + 552 WP_003597653.1 alpha/beta fold hydrolase -
OKB92_RS24390 (OKB92_24390) 5127801..5128187 + 387 WP_003597654.1 hypothetical protein -
OKB92_RS24395 (OKB92_24395) 5128321..5129343 - 1023 WP_265222457.1 TIGR01620 family protein -
OKB92_RS24400 (OKB92_24400) 5129340..5130788 - 1449 WP_003602557.1 YcjX family protein -
OKB92_RS24405 (OKB92_24405) 5130884..5131381 - 498 WP_265222458.1 RES family NAD+ phosphorylase Toxin
OKB92_RS24410 (OKB92_24410) 5131378..5131869 - 492 WP_056155356.1 DUF2384 domain-containing protein Antitoxin
OKB92_RS24415 (OKB92_24415) 5131933..5135310 - 3378 WP_265222459.1 PAS domain-containing protein -
OKB92_RS24420 (OKB92_24420) 5135307..5136743 - 1437 WP_265222460.1 O-antigen ligase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(5-151)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(35-96)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 17734.01 Da        Isoelectric Point: 5.2042

>T263188 WP_265222458.1 NZ_CP110131:c5131381-5130884 [Methylorubrum extorquens]
VSQSLWRIGTDARTYTADDLSGTGAKLSGGRWNAVGVALVYAAGSRALACLETFVHLNAGGLPLNRYLVEIDVPDEVWAS
AERATPDTLPVGWDAEPAGLVSLAFGTDWANGNRSALLLVPSVIVPEEQNALINPTHPDAAKITARKVRKWLYDPRLDRD
RGPFA

Download         Length: 498 bp

Antitoxin


Download         Length: 164 a.a.        Molecular weight: 17605.36 Da        Isoelectric Point: 8.9076

>AT263188 WP_056155356.1 NZ_CP110131:c5131869-5131378 [Methylorubrum extorquens]
MPDTMIKAPAKRRKPHGPGARPFAYLDLYRASPFDRIEVIKAGVPARAVKGFITALCLDQQVMFDALNLKTATVNKKAAR
DEALSSEDSERVVGLAKLVGQLEAMIEESGATKDFDAPGWLSRWLREPLPALGGGKPLDLLDTMEGQALVSRALAQIQSG
AYA

Download         Length: 492 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References