Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2340424..2341074 Replicon chromosome
Accession NZ_CP110131
Organism Methylorubrum extorquens strain NBC_00036

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OKB92_RS11400 Protein ID WP_182568766.1
Coordinates 2340424..2340678 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OKB92_RS11405 Protein ID WP_182568767.1
Coordinates 2340700..2341074 (+) Length 125 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OKB92_RS11375 (OKB92_11375) 2335742..2336074 + 333 WP_003601296.1 preprotein translocase subunit YajC -
OKB92_RS11380 (OKB92_11380) 2336142..2337740 + 1599 WP_012255346.1 protein translocase subunit SecD -
OKB92_RS11385 (OKB92_11385) 2337839..2338783 + 945 WP_265224501.1 protein translocase subunit SecF -
OKB92_RS11390 (OKB92_11390) 2338908..2339303 + 396 WP_265224503.1 MTH938/NDUFAF3 family protein -
OKB92_RS11395 (OKB92_11395) 2339437..2340333 + 897 WP_101475504.1 phytoene/squalene synthase family protein -
OKB92_RS11400 (OKB92_11400) 2340424..2340678 + 255 WP_182568766.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OKB92_RS11405 (OKB92_11405) 2340700..2341074 + 375 WP_182568767.1 helix-turn-helix transcriptional regulator Antitoxin
OKB92_RS11410 (OKB92_11410) 2341128..2342051 - 924 WP_003601302.1 manganese catalase family protein -
OKB92_RS11415 (OKB92_11415) 2342424..2344163 + 1740 WP_265224507.1 L-lactate permease -
OKB92_RS11420 (OKB92_11420) 2344236..2344679 - 444 WP_003601304.1 DUF983 domain-containing protein -
OKB92_RS11425 (OKB92_11425) 2344867..2345397 + 531 WP_265224510.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin

Cro/C1-type helix-turn-helix domain

(71-122)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9290.83 Da        Isoelectric Point: 9.9880

>T263186 WP_182568766.1 NZ_CP110131:2340424-2340678 [Methylorubrum extorquens]
MAEVVYSKAALRALTRLPADVSRKIRLKIEQYAAEPESLANNVKALRGEPGVLRLRVGDWRVLFTEEGVVVAVIKIAPRG
DAYD

Download         Length: 255 bp

Antitoxin


Download         Length: 125 a.a.        Molecular weight: 13111.79 Da        Isoelectric Point: 4.5106

>AT263186 WP_182568767.1 NZ_CP110131:2340700-2341074 [Methylorubrum extorquens]
MNPQIIITPGGERLVLVPEADFEALVAAAEDNADRTAVAEFRRKLAAGEEELVPASVVERLVSGENRVRVWREHRGLSGA
ALAKQAGLAQAYLSQIETGAREGTVETYGKLAAALSVSLDDLAG

Download         Length: 375 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References