263185

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 1150712..1151294 Replicon chromosome
Accession NZ_CP110131
Organism Methylorubrum extorquens strain NBC_00036

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag OKB92_RS05485 Protein ID WP_265223398.1
Coordinates 1150712..1150987 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID H1KK02
Locus tag OKB92_RS05490 Protein ID WP_003600760.1
Coordinates 1150977..1151294 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OKB92_RS05470 (OKB92_05470) 1147778..1148695 - 918 WP_012605511.1 cytochrome c family protein -
OKB92_RS05475 (OKB92_05475) 1149003..1149746 + 744 WP_265223396.1 3-deoxy-manno-octulosonate cytidylyltransferase -
OKB92_RS05480 (OKB92_05480) 1149763..1150620 + 858 WP_265223397.1 prephenate dehydratase -
OKB92_RS05485 (OKB92_05485) 1150712..1150987 + 276 WP_265223398.1 BrnT family toxin Toxin
OKB92_RS05490 (OKB92_05490) 1150977..1151294 + 318 WP_003600760.1 BrnA antitoxin family protein Antitoxin
OKB92_RS05495 (OKB92_05495) 1151402..1152010 - 609 WP_003600761.1 nucleotide exchange factor GrpE -
OKB92_RS05500 (OKB92_05500) 1152102..1154888 - 2787 WP_265223399.1 [protein-PII] uridylyltransferase -
OKB92_RS05505 (OKB92_05505) 1155048..1156022 + 975 WP_265223400.1 aliphatic sulfonate ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-84)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(28-100)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10033.51 Da        Isoelectric Point: 7.0130

>T263185 WP_265223398.1 NZ_CP110131:1150712-1150987 [Methylorubrum extorquens]
MLIVWDEPKRLTNLQKHGLDFADFEAGFDFETSLVAVAQPSAAGSARMKIIGEFDGQTVVAAIIAPLGREAISLISLRRA
SRSERRLYDAR

Download         Length: 276 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11641.04 Da        Isoelectric Point: 5.1832

>AT263185 WP_003600760.1 NZ_CP110131:1150977-1151294 [Methylorubrum extorquens]
MPADKPDRRPTTTSEEAGIQAGIAADPDNPEWTEADFRSAVPFEQAFPVLAEKLRRTRGPQSAPTKQLVSLRLDQDVLLR
FRATGPGWQSRMNEALRRAAADLPD

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB H1KK02

References