263182

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2811010..2811602 Replicon chromosome
Accession NZ_CP110130
Organism Methylorubrum extorquens strain NBC_00404

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag OKC48_RS13125 Protein ID WP_265221661.1
Coordinates 2811300..2811602 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag OKC48_RS13120 Protein ID WP_265221662.1
Coordinates 2811010..2811303 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OKC48_RS13100 (OKC48_13100) 2806834..2807781 + 948 WP_238506802.1 fatty acid desaturase -
OKC48_RS13105 (OKC48_13105) 2807851..2809122 - 1272 WP_265221665.1 tyrosine--tRNA ligase -
OKC48_RS13110 (OKC48_13110) 2809263..2810396 + 1134 WP_265221664.1 anhydro-N-acetylmuramic acid kinase -
OKC48_RS13115 (OKC48_13115) 2810393..2811016 + 624 WP_265221663.1 DUF3578 domain-containing protein -
OKC48_RS13120 (OKC48_13120) 2811010..2811303 - 294 WP_265221662.1 putative addiction module antidote protein Antitoxin
OKC48_RS13125 (OKC48_13125) 2811300..2811602 - 303 WP_265221661.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OKC48_RS13130 (OKC48_13130) 2811724..2812824 + 1101 WP_265221660.1 chorismate synthase -
OKC48_RS13135 (OKC48_13135) 2812953..2814032 + 1080 WP_015823256.1 3,4-dihydroxy-2-butanone-4-phosphate synthase -
OKC48_RS13140 (OKC48_13140) 2814187..2815038 - 852 WP_265221659.1 histone deacetylase family protein -
OKC48_RS13145 (OKC48_13145) 2815170..2815418 - 249 WP_265221658.1 hypothetical protein -
OKC48_RS13150 (OKC48_13150) 2815417..2816055 + 639 WP_265221657.1 L,D-transpeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-90)

Antitoxin

Uncharacterized protein HI1420

(2-92)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11129.87 Da        Isoelectric Point: 10.2636

>T263182 WP_265221661.1 NZ_CP110130:c2811602-2811300 [Methylorubrum extorquens]
MLEIIRTRTFADWLKGLRDDRAKARIALRIDRLALGHEGDSKAVGGGVSELRIDYGPGYRIYFTYRGKTLVVLLCGGDKA
SQKRDISRAKTLATMLDGTE

Download         Length: 303 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10378.56 Da        Isoelectric Point: 4.2220

>AT263182 WP_265221662.1 NZ_CP110130:c2811303-2811010 [Methylorubrum extorquens]
MMTETSPYDSAEFLESDEAVAEYLAAAIEEGDAALFRRALGVAARARGMTQIARETGLSRESLYRALSDDGNPSLDTALR
VLNALNVRLTASVASPQ

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References