263181

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ParST/RES-Xre
Location 1337517..1338502 Replicon chromosome
Accession NZ_CP110130
Organism Methylorubrum extorquens strain NBC_00404

Toxin (Protein)


Gene name ParT Uniprot ID -
Locus tag OKC48_RS06185 Protein ID WP_265222458.1
Coordinates 1338005..1338502 (+) Length 166 a.a.

Antitoxin (Protein)


Gene name ParS Uniprot ID -
Locus tag OKC48_RS06180 Protein ID WP_056155356.1
Coordinates 1337517..1338008 (+) Length 164 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OKC48_RS06170 (OKC48_06170) 1332643..1334079 + 1437 WP_265222460.1 O-antigen ligase family protein -
OKC48_RS06175 (OKC48_06175) 1334076..1337453 + 3378 WP_265222459.1 PAS domain-containing protein -
OKC48_RS06180 (OKC48_06180) 1337517..1338008 + 492 WP_056155356.1 DUF2384 domain-containing protein Antitoxin
OKC48_RS06185 (OKC48_06185) 1338005..1338502 + 498 WP_265222458.1 RES family NAD+ phosphorylase Toxin
OKC48_RS06190 (OKC48_06190) 1338598..1340046 + 1449 WP_265245126.1 YcjX family protein -
OKC48_RS06195 (OKC48_06195) 1340043..1341065 + 1023 WP_265222457.1 TIGR01620 family protein -
OKC48_RS06200 (OKC48_06200) 1341199..1341585 - 387 WP_003597654.1 hypothetical protein -
OKC48_RS06205 (OKC48_06205) 1341807..1342358 - 552 WP_003597653.1 alpha/beta fold hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(5-151)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(35-96)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 17734.01 Da        Isoelectric Point: 5.2042

>T263181 WP_265222458.1 NZ_CP110130:1338005-1338502 [Methylorubrum extorquens]
VSQSLWRIGTDARTYTADDLSGTGAKLSGGRWNAVGVALVYAAGSRALACLETFVHLNAGGLPLNRYLVEIDVPDEVWAS
AERATPDTLPVGWDAEPAGLVSLAFGTDWANGNRSALLLVPSVIVPEEQNALINPTHPDAAKITARKVRKWLYDPRLDRD
RGPFA

Download         Length: 498 bp

Antitoxin


Download         Length: 164 a.a.        Molecular weight: 17605.36 Da        Isoelectric Point: 8.9076

>AT263181 WP_056155356.1 NZ_CP110130:1337517-1338008 [Methylorubrum extorquens]
MPDTMIKAPAKRRKPHGPGARPFAYLDLYRASPFDRIEVIKAGVPARAVKGFITALCLDQQVMFDALNLKTATVNKKAAR
DEALSSEDSERVVGLAKLVGQLEAMIEESGATKDFDAPGWLSRWLREPLPALGGGKPLDLLDTMEGQALVSRALAQIQSG
AYA

Download         Length: 492 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References