263179

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 1011036..1011571 Replicon chromosome
Accession NZ_CP110130
Organism Methylorubrum extorquens strain NBC_00404

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag OKC48_RS04725 Protein ID WP_265245068.1
Coordinates 1011281..1011571 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag OKC48_RS04720 Protein ID WP_265222623.1
Coordinates 1011036..1011284 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OKC48_RS04705 (OKC48_04705) 1006254..1007837 - 1584 WP_265222626.1 DUF5691 domain-containing protein -
OKC48_RS04710 (OKC48_04710) 1007837..1009204 - 1368 WP_265222625.1 SWIM zinc finger family protein -
OKC48_RS04715 (OKC48_04715) 1009400..1010902 - 1503 WP_265245067.1 glucose-6-phosphate dehydrogenase -
OKC48_RS04720 (OKC48_04720) 1011036..1011284 + 249 WP_265222623.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
OKC48_RS04725 (OKC48_04725) 1011281..1011571 + 291 WP_265245068.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OKC48_RS04730 (OKC48_04730) 1011629..1012291 + 663 WP_265222621.1 uracil-DNA glycosylase family protein -
OKC48_RS04735 (OKC48_04735) 1012299..1013825 - 1527 WP_265245069.1 alginate export family protein -
OKC48_RS04740 (OKC48_04740) 1014150..1014848 + 699 WP_265222618.1 orotidine-5'-phosphate decarboxylase -
OKC48_RS04745 (OKC48_04745) 1014851..1015195 + 345 WP_003605408.1 DUF1330 domain-containing protein -
OKC48_RS04750 (OKC48_04750) 1015213..1015836 - 624 WP_265222617.1 TetR/AcrR family transcriptional regulator -
OKC48_RS04755 (OKC48_04755) 1016059..1016259 - 201 WP_003605412.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

Antitoxin ParD

(1-81)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11054.59 Da        Isoelectric Point: 10.8582

>T263179 WP_265245068.1 NZ_CP110130:1011281-1011571 [Methylorubrum extorquens]
MSVRLSPRARGDLSRIWDDSAERWGADQADRYIRLRAGGFDRLAEDPARGLRADEIRKGYFRLSVGSHVLFYRLGAEGGI
EVIRILHGRMDFKRHL

Download         Length: 291 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9024.95 Da        Isoelectric Point: 4.5292

>AT263179 WP_265222623.1 NZ_CP110130:1011036-1011284 [Methylorubrum extorquens]
MSRNTSVSLGEHFAQFIDRQVEGGRYGSASEVVRAGLRLLEEQEAALNTLRAALIEGEESGSPEPFDTETFLREKREGAI
RG

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References