Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 5112532..5113136 Replicon chromosome
Accession NZ_CP110128
Organism Pseudomonas sp. WJP1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag OH720_RS23045 Protein ID WP_272603024.1
Coordinates 5112532..5112825 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag OH720_RS23050 Protein ID WP_272603025.1
Coordinates 5112828..5113136 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH720_RS23030 (OH720_23035) 5108173..5108481 + 309 WP_008056246.1 DUF485 domain-containing protein -
OH720_RS23035 (OH720_23040) 5108478..5110124 + 1647 WP_272603022.1 cation acetate symporter -
OH720_RS23040 (OH720_23045) 5110186..5112240 + 2055 WP_272603023.1 phenylacetic acid degradation bifunctional protein PaaZ -
OH720_RS23045 (OH720_23050) 5112532..5112825 + 294 WP_272603024.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OH720_RS23050 (OH720_23055) 5112828..5113136 + 309 WP_272603025.1 putative addiction module antidote protein Antitoxin
OH720_RS23055 (OH720_23060) 5113646..5113960 + 315 WP_272603026.1 hypothetical protein -
OH720_RS23060 (OH720_23065) 5114105..5114956 - 852 WP_272603027.1 helix-turn-helix transcriptional regulator -
OH720_RS23065 (OH720_23070) 5115010..5116428 - 1419 WP_272603028.1 aminotransferase -
OH720_RS23070 (OH720_23075) 5116468..5117574 - 1107 WP_272603029.1 polyamine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(5-96)

Antitoxin

Uncharacterized protein HI1420

(5-91)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10721.52 Da        Isoelectric Point: 10.7649

>T263176 WP_272603024.1 NZ_CP110128:5112532-5112825 [Pseudomonas sp. WJP1]
MNYLVQQTAIFSAWHTSIRDLRARIAIARRIERACAGNLGDIKPVGDGVSEMRVDVGAGYRIYFTMRKTVVIVLLAGGDK
SSQNADIKRAKKLAKEV

Download         Length: 294 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11000.51 Da        Isoelectric Point: 6.2093

>AT263176 WP_272603025.1 NZ_CP110128:5112828-5113136 [Pseudomonas sp. WJP1]
MSQTLTTFDMAALLDSDEAISEYLSQVLADGDNEEFLRAVGYVVKARGMTQVAKNSGMGRESLYKAFAPGAKPRFNTVLK
VIHALGIDLCAQPGHVINHSNS

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References