Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-DUF971
Location 3767906..3768498 Replicon chromosome
Accession NZ_CP110128
Organism Pseudomonas sp. WJP1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag OH720_RS16840 Protein ID WP_272602095.1
Coordinates 3768199..3768498 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag OH720_RS16835 Protein ID WP_272602094.1
Coordinates 3767906..3768202 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH720_RS16805 (OH720_16810) 3762917..3763501 + 585 WP_272602088.1 hypothetical protein -
OH720_RS16810 (OH720_16815) 3763574..3764656 - 1083 WP_272602089.1 AI-2E family transporter -
OH720_RS16815 (OH720_16820) 3765013..3765450 + 438 WP_272602090.1 hypothetical protein -
OH720_RS16820 (OH720_16825) 3765754..3766581 - 828 WP_272602091.1 DUF3618 domain-containing protein -
OH720_RS16825 (OH720_16830) 3766578..3767009 - 432 WP_272602092.1 phage holin family protein -
OH720_RS16830 (OH720_16835) 3767009..3767659 - 651 WP_272602093.1 hypothetical protein -
OH720_RS16835 (OH720_16840) 3767906..3768202 - 297 WP_272602094.1 putative addiction module antidote protein Antitoxin
OH720_RS16840 (OH720_16845) 3768199..3768498 - 300 WP_272602095.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OH720_RS16845 (OH720_16850) 3768660..3769262 - 603 WP_272602096.1 hypothetical protein -
OH720_RS16850 (OH720_16855) 3769403..3770359 - 957 WP_272602097.1 threonine dehydratase -
OH720_RS16855 (OH720_16860) 3770465..3771271 + 807 WP_272602098.1 AraC family transcriptional regulator -
OH720_RS16860 (OH720_16865) 3771268..3771963 - 696 WP_272602099.1 tRNA (adenine(22)-N(1))-methyltransferase TrmK -
OH720_RS16865 (OH720_16870) 3772167..3772463 + 297 WP_272602100.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(47-90)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11148.78 Da        Isoelectric Point: 10.0625

>T263175 WP_272602095.1 NZ_CP110128:c3768498-3768199 [Pseudomonas sp. WJP1]
MKTIKQTATYMTWERKLKDQRAKAAIAARIFRLANGLLGDVSPVGQGVSELRIHYGPGYRVYFQQRGDEFVLLLCGGDKS
SQSRDIEAAKILASEWRSE

Download         Length: 300 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10615.16 Da        Isoelectric Point: 4.5994

>AT263175 WP_272602094.1 NZ_CP110128:c3768202-3767906 [Pseudomonas sp. WJP1]
MSEKIYDYDPAAALDGPEAIAVFMADAFETGNAEYIAKAMGVVARAKGMTELARETGLSREQLYRSFSEDGNPTLKTMLA
VMRALGIDMTARPHVSPL

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References