Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 424473..425062 Replicon chromosome
Accession NZ_CP110128
Organism Pseudomonas sp. WJP1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag OH720_RS01925 Protein ID WP_272604350.1
Coordinates 424473..424778 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OH720_RS01930 Protein ID WP_007943750.1
Coordinates 424775..425062 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH720_RS01900 (OH720_01900) 419699..420529 + 831 WP_272604345.1 type II secretion system protein GspK -
OH720_RS01905 (OH720_01905) 420526..421632 + 1107 WP_272604346.1 type II secretion system protein GspL -
OH720_RS01910 (OH720_01910) 421629..422090 + 462 WP_272604347.1 type II secretion system protein GspM -
OH720_RS01915 (OH720_01915) 422083..423363 - 1281 WP_272604348.1 MFS transporter -
OH720_RS01920 (OH720_01920) 423483..424385 + 903 WP_272604349.1 LysR family transcriptional regulator -
OH720_RS01925 (OH720_01925) 424473..424778 + 306 WP_272604350.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OH720_RS01930 (OH720_01930) 424775..425062 + 288 WP_007943750.1 putative addiction module antidote protein Antitoxin
OH720_RS01935 (OH720_01935) 425209..426435 - 1227 WP_272604351.1 beta-ketoacyl-ACP synthase -
OH720_RS01940 (OH720_01940) 426435..427163 - 729 WP_008058155.1 3-oxoacyl-ACP reductase FabG -
OH720_RS01945 (OH720_01945) 427160..427621 - 462 WP_272604352.1 hotdog family protein -
OH720_RS01950 (OH720_01950) 427618..428814 - 1197 WP_272604353.1 beta-ketoacyl-[acyl-carrier-protein] synthase family protein -
OH720_RS01955 (OH720_01955) 428811..429293 - 483 WP_272604354.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(3-95)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11397.05 Da        Isoelectric Point: 9.9969

>T263172 WP_272604350.1 NZ_CP110128:424473-424778 [Pseudomonas sp. WJP1]
MTEILRSSTFSGWLLKLADSRARMRIQVRIDRMADGNFGDVKAIGEGLSEARIDYGPGYRVYFMQQGSQLVILLCGGDKS
SQTRDIKQARLIAKSWQEQNP

Download         Length: 306 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10372.72 Da        Isoelectric Point: 4.6412

>AT263172 WP_007943750.1 NZ_CP110128:424775-425062 [Pseudomonas sp. WJP1]
MTEQFTRWDSAEYLKTEEDMANYLDACMEEAGDDPAFIAKALGTIARARGMTQVARDAGLSRESLYRALSGEGNPEFGTI
LKVVKALGLKLHAST

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References