Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2233122..2233290 Replicon chromosome
Accession NZ_CP110123
Organism Klebsiella michiganensis strain MX581

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2233180..2233283 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2233122..2233290 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OKE89_RS10715 (OKE89_10715) 2228249..2230309 + 2061 WP_009652043.1 oligopeptidase B -
OKE89_RS10720 (OKE89_10720) 2230316..2230975 - 660 WP_004852093.1 exodeoxyribonuclease X -
OKE89_RS10725 (OKE89_10725) 2231054..2231284 - 231 WP_004103351.1 DNA polymerase III subunit theta -
OKE89_RS10730 (OKE89_10730) 2231420..2231794 + 375 WP_004852090.1 CopC domain-containing protein YobA -
OKE89_RS10735 (OKE89_10735) 2231799..2232668 + 870 WP_004852088.1 copper homeostasis membrane protein CopD -
OKE89_RS10740 (OKE89_10740) 2232685..2233023 + 339 WP_049106124.1 YebY family protein -
- 2233122..2233290 - 169 - - Antitoxin
- 2233180..2233283 + 104 - - Toxin
OKE89_RS10745 (OKE89_10745) 2233408..2234367 - 960 WP_049106125.1 spore coat protein U domain-containing protein -
OKE89_RS10750 (OKE89_10750) 2234382..2236712 - 2331 WP_064402597.1 fimbria/pilus outer membrane usher protein -
OKE89_RS10755 (OKE89_10755) 2236715..2237479 - 765 WP_049106126.1 fimbria/pilus periplasmic chaperone -
OKE89_RS10760 (OKE89_10760) 2237498..2238016 - 519 WP_004852079.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T263162 NZ_CP110123:2233180-2233283 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT263162 NZ_CP110123:c2233290-2233122 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References