Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 46837..47402 Replicon plasmid pYA7-1a
Accession NZ_CP110115
Organism Arthrobacter sp. YA7-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OIT41_RS20035 Protein ID WP_264638080.1
Coordinates 47109..47402 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OIT41_RS20030 Protein ID WP_241710795.1
Coordinates 46837..47112 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OIT41_RS20010 (OIT41_20010) 43008..44141 + 1134 WP_264636462.1 site-specific integrase -
OIT41_RS20015 (OIT41_20015) 44134..44487 + 354 WP_264636463.1 helix-turn-helix transcriptional regulator -
OIT41_RS20020 (OIT41_20020) 44480..45946 + 1467 WP_264638079.1 Fis family transcriptional regulator -
OIT41_RS20025 (OIT41_20025) 46087..46734 + 648 WP_264636465.1 hypothetical protein -
OIT41_RS20030 (OIT41_20030) 46837..47112 + 276 WP_241710795.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OIT41_RS20035 (OIT41_20035) 47109..47402 + 294 WP_264638080.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OIT41_RS20040 (OIT41_20040) 48429..49655 - 1227 WP_241710794.1 ATP-binding protein -
OIT41_RS20045 (OIT41_20045) 49954..50276 + 323 Protein_42 hypothetical protein -
OIT41_RS20050 (OIT41_20050) 50358..50660 - 303 WP_241710793.1 DUF4193 domain-containing protein -
OIT41_RS20055 (OIT41_20055) 50904..52136 - 1233 WP_241710792.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..129773 129773


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-94)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10886.48 Da        Isoelectric Point: 10.7271

>T263126 WP_264638080.1 NZ_CP110115:47109-47402 [Arthrobacter sp. YA7-1]
VTGAESTGPSPWNVEVTSPALRGFRRLPEKAAAAIVEFVTGALARNPHRLSKPLTNGLLGLRTARRGDYRVLFTLDIEEH
ILYVHRIEHRSDVYKPR

Download         Length: 294 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10170.38 Da        Isoelectric Point: 4.8676

>AT263126 WP_241710795.1 NZ_CP110115:46837-47112 [Arthrobacter sp. YA7-1]
MRTVPLSEAKDKLSALVEEADTTHEIIQITRHGHPSAVLMSADDLESLQETIHWLSQPGIREDLDQARRDIVDGKTTSGA
DLRREFGLPPR

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References