Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-StbC
Location 1005821..1006488 Replicon chromosome
Accession NZ_CP110110
Organism Stutzerimonas balearica strain Z8

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag D3P44_RS04695 Protein ID WP_212739827.1
Coordinates 1005821..1006246 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag D3P44_RS04700 Protein ID WP_200628058.1
Coordinates 1006243..1006488 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D3P44_RS04665 (D3P44_004665) 1001038..1001601 - 564 WP_043218847.1 hypothetical protein -
D3P44_RS04670 (D3P44_004670) 1001751..1002539 + 789 WP_041107591.1 trehalose-phosphatase -
D3P44_RS04675 (D3P44_004675) 1002536..1003924 + 1389 WP_043218848.1 alpha,alpha-trehalose-phosphate synthase (UDP-forming) -
D3P44_RS04680 (D3P44_004680) 1004010..1004654 + 645 WP_041107521.1 carbonate dehydratase -
D3P44_RS04685 (D3P44_004685) 1004678..1005562 + 885 WP_043218850.1 DMT family transporter -
D3P44_RS04695 (D3P44_004695) 1005821..1006246 - 426 WP_212739827.1 type II toxin-antitoxin system VapC family toxin Toxin
D3P44_RS04700 (D3P44_004700) 1006243..1006488 - 246 WP_200628058.1 plasmid stabilization protein Antitoxin
D3P44_RS04705 (D3P44_004705) 1006978..1007307 + 330 WP_212739828.1 hypothetical protein -
D3P44_RS04710 (D3P44_004710) 1007369..1008007 + 639 WP_212739829.1 hypothetical protein -
D3P44_RS04715 (D3P44_004715) 1008065..1009369 + 1305 WP_010793081.1 IS1380-like element ISPa33 family transposase -
D3P44_RS04720 (D3P44_004720) 1009462..1010199 + 738 WP_268845839.1 hypothetical protein -
D3P44_RS04725 (D3P44_004725) 1010508..1010903 - 396 WP_043218856.1 MerR family DNA-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15091.33 Da        Isoelectric Point: 4.4829

>T263123 WP_212739827.1 NZ_CP110110:c1006246-1005821 [Stutzerimonas balearica]
MILLDTNVLSELMRAKPAPQVLEWVDAQPASELAISAITVAEILYGIARMPDGKRKQGLLDIASAMFEEDFAGNILPFDA
DAAVHYAEIAAATEAKGRIVDMADAQIAAIGRLHDAVIATRNARHFEPLGVALVDPWSGRG

Download         Length: 426 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8958.24 Da        Isoelectric Point: 10.8838

>AT263123 WP_200628058.1 NZ_CP110110:c1006488-1006243 [Stutzerimonas balearica]
MASITIRNLDDDLKAKLRVLAASHGRSMEEEARIIIRQALSRQEKRGGLGTRIHSRFASVGGVDLALPERKDKARAASFD
E

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References