Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 1379944..1380551 Replicon chromosome
Accession NZ_CP110108
Organism Alcaligenes sp. SMD-FA

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OKX01_RS06330 Protein ID WP_264672635.1
Coordinates 1380246..1380551 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OKX01_RS06325 Protein ID WP_264672634.1
Coordinates 1379944..1380249 (-) Length 102 a.a.

Genomic Context

OKX01_RS06310OKX01_RS06315OKX01_RS06320OKX01_RS06335OKX01_RS06340OKX01_RS06345OKX01_RS06355OKX01_RS06300OKX01_RS06325OKX01_RS06330OKX01_RS06350
Location: 1376953..1378173 (1221 bp)
Type: Others
Protein ID: Protein_1224
Location: 1378381..1379262 (882 bp)
Type: Others
Protein ID: WP_264672632.1
Location: 1379268..1379738 (471 bp)
Type: Others
Protein ID: WP_264672633.1
Location: 1381071..1382447 (1377 bp)
Type: Others
Protein ID: WP_264672636.1
Location: 1382706..1383281 (576 bp)
Type: Others
Protein ID: WP_108727216.1
Location: 1383369..1383470 (102 bp)
Type: Others
Protein ID: Protein_1231
Location: 1384317..1385189 (873 bp)
Type: Others
Protein ID: WP_094196162.1
Location: 1375046..1376449 (1404 bp)
Type: Others
Protein ID: WP_264672631.1
Location: 1379944..1380249 (306 bp)
Type: Antitoxin
Protein ID: WP_264672634.1
Location: 1380246..1380551 (306 bp)
Type: Toxin
Protein ID: WP_264672635.1
Location: 1383509..1384213 (705 bp)
Type: Others
Protein ID: WP_125277628.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
OKX01_RS06300 (OKX01_06300)1375046..1376449-1404WP_264672631.1GntP family permease-
OKX01_RS06310 (OKX01_06310)1376953..1378173+1221Protein_1224IS3 family transposase-
OKX01_RS06315 (OKX01_06315)1378381..1379262+882WP_264672632.1hypothetical protein-
OKX01_RS06320 (OKX01_06320)1379268..1379738+471WP_264672633.1hypothetical protein-
OKX01_RS06325 (OKX01_06325)1379944..1380249-306WP_264672634.1putative addiction module antidote proteinAntitoxin
OKX01_RS06330 (OKX01_06330)1380246..1380551-306WP_264672635.1type II toxin-antitoxin system RelE/ParE family toxinToxin
OKX01_RS06335 (OKX01_06335)1381071..1382447+1377WP_264672636.1FAD-dependent oxidoreductase-
OKX01_RS06340 (OKX01_06340)1382706..1383281+576WP_108727216.1TetR/AcrR family transcriptional regulator-
OKX01_RS06345 (OKX01_06345)1383369..1383470+102Protein_1231hypothetical protein-
OKX01_RS06350 (OKX01_06350)1383509..1384213-705WP_125277628.1SDR family oxidoreductase-
OKX01_RS06355 (OKX01_06355)1384317..1385189+873WP_094196162.1LysR substrate-binding domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(19-88)

Antitoxin

Uncharacterized protein HI1420

(3-94)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11497.26 Da        Isoelectric Point: 10.2587

>T263120 WP_264672635.1 NZ_CP110108:c1380551-1380246 [Alcaligenes sp. SMD-FA]
MNTINRSETFSTWLIGLKDLKARAKIVVRIKQASLGNFGDVKPISDGVYEMRIHFGPGYRLYYAREGRVVYLLLSGGDKS
SQKQDIKTAIAMWKQIQEDQS

Download         Length: 306 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10735.34 Da        Isoelectric Point: 4.8411

>AT263120 WP_264672634.1 NZ_CP110108:c1380249-1379944 [Alcaligenes sp. SMD-FA]
MTTIKTAPFDAAEYLDSEEAIAEYLSAALEEDDPALFLSALADVVKARGMTKMAKDAGVGRESLYKALAPGAKPRYDTVL
KLARAAGVKLTVEPISRCNAT

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References