Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 1379944..1380551 Replicon chromosome
Accession NZ_CP110108
Organism Alcaligenes sp. SMD-FA

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OKX01_RS06330 Protein ID WP_264672635.1
Coordinates 1380246..1380551 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OKX01_RS06325 Protein ID WP_264672634.1
Coordinates 1379944..1380249 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OKX01_RS06300 (OKX01_06300) 1375046..1376449 - 1404 WP_264672631.1 GntP family permease -
OKX01_RS06310 (OKX01_06310) 1376953..1378173 + 1221 Protein_1224 IS3 family transposase -
OKX01_RS06315 (OKX01_06315) 1378381..1379262 + 882 WP_264672632.1 hypothetical protein -
OKX01_RS06320 (OKX01_06320) 1379268..1379738 + 471 WP_264672633.1 hypothetical protein -
OKX01_RS06325 (OKX01_06325) 1379944..1380249 - 306 WP_264672634.1 putative addiction module antidote protein Antitoxin
OKX01_RS06330 (OKX01_06330) 1380246..1380551 - 306 WP_264672635.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OKX01_RS06335 (OKX01_06335) 1381071..1382447 + 1377 WP_264672636.1 FAD-dependent oxidoreductase -
OKX01_RS06340 (OKX01_06340) 1382706..1383281 + 576 WP_108727216.1 TetR/AcrR family transcriptional regulator -
OKX01_RS06345 (OKX01_06345) 1383369..1383470 + 102 Protein_1231 hypothetical protein -
OKX01_RS06350 (OKX01_06350) 1383509..1384213 - 705 WP_125277628.1 SDR family oxidoreductase -
OKX01_RS06355 (OKX01_06355) 1384317..1385189 + 873 WP_094196162.1 LysR substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(19-88)

Antitoxin

Uncharacterized protein HI1420

(3-94)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11497.26 Da        Isoelectric Point: 10.2587

>T263120 WP_264672635.1 NZ_CP110108:c1380551-1380246 [Alcaligenes sp. SMD-FA]
MNTINRSETFSTWLIGLKDLKARAKIVVRIKQASLGNFGDVKPISDGVYEMRIHFGPGYRLYYAREGRVVYLLLSGGDKS
SQKQDIKTAIAMWKQIQEDQS

Download         Length: 306 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10735.34 Da        Isoelectric Point: 4.8411

>AT263120 WP_264672634.1 NZ_CP110108:c1380249-1379944 [Alcaligenes sp. SMD-FA]
MTTIKTAPFDAAEYLDSEEAIAEYLSAALEEDDPALFLSALADVVKARGMTKMAKDAGVGRESLYKALAPGAKPRYDTVL
KLARAAGVKLTVEPISRCNAT

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References