Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 2260873..2261431 Replicon chromosome
Accession NZ_CP110087
Organism Moraxella bovis strain SAM109242

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP095_RS11475 Protein ID WP_228157760.1
Coordinates 2260873..2261145 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP095_RS11480 Protein ID WP_264677330.1
Coordinates 2261138..2261431 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP095_RS11430 (LP095_11430) 2256204..2256440 + 237 WP_078275185.1 sulfurtransferase TusA -
LP095_RS11435 (LP095_11435) 2256443..2257009 + 567 WP_078275186.1 hypothetical protein -
LP095_RS11440 (LP095_11440) 2257006..2257536 - 531 WP_264678418.1 glucose-6-phosphate 1-dehydrogenase family protein -
LP095_RS11445 (LP095_11445) 2257659..2258051 - 393 WP_264677325.1 type II toxin-antitoxin system VapC family toxin -
LP095_RS11450 (LP095_11450) 2258048..2258311 - 264 WP_264675982.1 type II toxin-antitoxin system VapB family antitoxin -
LP095_RS11455 (LP095_11455) 2258391..2259650 - 1260 WP_264677326.1 replication-associated recombination protein A -
LP095_RS11460 (LP095_11460) 2259647..2260027 - 381 WP_264677327.1 type II toxin-antitoxin system VapC family toxin -
LP095_RS11465 (LP095_11465) 2260024..2260293 - 270 WP_264677328.1 hypothetical protein -
LP095_RS11470 (LP095_11470) 2260353..2260808 + 456 WP_264677329.1 type IV secretion protein Rhs -
LP095_RS11475 (LP095_11475) 2260873..2261145 - 273 WP_228157760.1 type II toxin-antitoxin system YafQ family toxin Toxin
LP095_RS11480 (LP095_11480) 2261138..2261431 - 294 WP_264677330.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP095_RS11485 (LP095_11485) 2261575..2262909 - 1335 WP_264677331.1 deoxyguanosinetriphosphate triphosphohydrolase -
LP095_RS11490 (LP095_11490) 2263029..2263232 - 204 WP_115368689.1 hypothetical protein -
LP095_RS11495 (LP095_11495) 2263222..2263572 - 351 WP_181879486.1 PIN domain protein -
LP095_RS11500 (LP095_11500) 2263679..2264290 - 612 WP_115368690.1 methyltransferase -
LP095_RS11505 (LP095_11505) 2264411..2265715 + 1305 WP_264677332.1 valine--pyruvate transaminase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(6-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-52)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10415.99 Da        Isoelectric Point: 6.9668

>T263104 WP_228157760.1 NZ_CP110087:c2261145-2260873 [Moraxella bovis]
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG

Download         Length: 273 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11096.37 Da        Isoelectric Point: 4.7769

>AT263104 WP_264677330.1 NZ_CP110087:c2261431-2261138 [Moraxella bovis]
MSHTNFNMRLDNDLRQKVYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References