Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 1979866..1980442 Replicon chromosome
Accession NZ_CP110087
Organism Moraxella bovis strain SAM109242

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag LP095_RS10045 Protein ID WP_264676341.1
Coordinates 1979866..1980126 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag LP095_RS10050 Protein ID WP_078273964.1
Coordinates 1980107..1980442 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP095_RS10030 (LP095_10030) 1974897..1976972 + 2076 WP_264677152.1 NAD-dependent DNA ligase LigA -
LP095_RS10035 (LP095_10035) 1977484..1978869 + 1386 WP_078273966.1 APC family permease -
LP095_RS10040 (LP095_10040) 1978959..1979667 - 709 Protein_1973 ParA family protein -
LP095_RS10045 (LP095_10045) 1979866..1980126 + 261 WP_264676341.1 type II toxin-antitoxin system HicA family toxin Toxin
LP095_RS10050 (LP095_10050) 1980107..1980442 + 336 WP_078273964.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
LP095_RS10055 (LP095_10055) 1980626..1981210 - 585 Protein_1976 TetR/AcrR family transcriptional regulator -
LP095_RS10060 (LP095_10060) 1981473..1982654 + 1182 WP_264678410.1 fatty acid desaturase -
LP095_RS10065 (LP095_10065) 1983301..1983651 + 351 WP_264677153.1 hypothetical protein -
LP095_RS10070 (LP095_10070) 1983663..1984097 + 435 WP_268193501.1 carbonic anhydrase family protein -
LP095_RS10075 (LP095_10075) 1984201..1985283 + 1083 WP_264677155.1 tRNA pseudouridine(13) synthase TruD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Uncharacterised protein family HicB

(54-104)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9551.46 Da        Isoelectric Point: 4.3376

>T263102 WP_264676341.1 NZ_CP110087:1979866-1980126 [Moraxella bovis]
IEALFVALGADISERAGSRMAVALNGQVMVFHRPHPSPNTDKSAVMSIRKWLDGMGITPLDDDSQTDEYADKQTDEQEQT
HEHNDN

Download         Length: 261 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12189.67 Da        Isoelectric Point: 4.5658

>AT263102 WP_078273964.1 NZ_CP110087:1980107-1980442 [Moraxella bovis]
MNTMTINNHKALITFDSELGLFRGEFIGLNGGADFYADSVDGLNEQGALSLQAFLDVCQEQGISPYQSYSGKFVTRLPKE
LHQKIAETATAKGISLNQWINETLSREVGFA

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References