Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) AbkB-shpB/BrnT-BrnA
Location 926191..926743 Replicon chromosome
Accession NZ_CP110087
Organism Moraxella bovis strain SAM109242

Toxin (Protein)


Gene name AbkB Uniprot ID A0A1T0A7D3
Locus tag LP095_RS04760 Protein ID WP_029102268.1
Coordinates 926465..926743 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag LP095_RS04755 Protein ID WP_078273473.1
Coordinates 926191..926478 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP095_RS04735 (LP095_04735) 921605..922654 + 1050 WP_264678112.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
LP095_RS04740 (LP095_04740) 922733..924253 + 1521 WP_264678113.1 DUF389 domain-containing protein -
LP095_RS04745 (LP095_04745) 924282..924407 + 126 WP_264676709.1 hypothetical protein -
LP095_RS04750 (LP095_04750) 924451..926181 - 1731 WP_078273474.1 flotillin domain-containing protein -
LP095_RS04755 (LP095_04755) 926191..926478 - 288 WP_078273473.1 BrnA antitoxin family protein Antitoxin
LP095_RS04760 (LP095_04760) 926465..926743 - 279 WP_029102268.1 BrnT family toxin Toxin
LP095_RS04765 (LP095_04765) 926838..927494 - 657 WP_264678114.1 YqiJ family protein -
LP095_RS04770 (LP095_04770) 927694..928359 - 666 WP_264678115.1 PspA/IM30 family protein -
LP095_RS04775 (LP095_04775) 928572..928754 - 183 WP_264683628.1 hypothetical protein -
LP095_RS04780 (LP095_04780) 928855..929370 - 516 WP_264678117.1 hypothetical protein -
LP095_RS04785 (LP095_04785) 929518..929868 - 351 WP_078273468.1 TIGR01244 family sulfur transferase -
LP095_RS04790 (LP095_04790) 929981..930757 + 777 WP_264678118.1 nucleotidyltransferase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-85)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(36-89)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10484.81 Da        Isoelectric Point: 5.1084

>T263100 WP_029102268.1 NZ_CP110087:c926743-926465 [Moraxella bovis]
MIFEWDDNKNRTNKQKHGVSFESASRIFLDPFLIVTEDTSSDEVRWLGVGSVDGVVILLVVHTHTDTDGTEIIRIISARK
LSRGEIERYGYC

Download         Length: 279 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10979.71 Da        Isoelectric Point: 7.0097

>AT263100 WP_078273473.1 NZ_CP110087:c926478-926191 [Moraxella bovis]
MAIVRKTLDDIKHTPIDKDELAQLQSMSDDSINYDDIPPLTDVQIANLRLYKPIKQQITLRLDSDIVAWLKKDGKGYQTR
ANQLLRQLMLKELTT

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1T0A7D3

Antitoxin

Source ID Structure

References