Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 762091..762668 Replicon chromosome
Accession NZ_CP110087
Organism Moraxella bovis strain SAM109242

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP095_RS04010 Protein ID WP_078275234.1
Coordinates 762333..762668 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP095_RS04005 Protein ID WP_078275235.1
Coordinates 762091..762333 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP095_RS03985 (LP095_03985) 757711..758433 + 723 WP_264678018.1 tRNA pseudouridine(65) synthase TruC -
LP095_RS03990 (LP095_03990) 758681..759643 - 963 Protein_782 RNA-guided endonuclease TnpB family protein -
LP095_RS03995 (LP095_03995) 759853..760465 - 613 Protein_783 IS607 family transposase -
LP095_RS04000 (LP095_04000) 760805..761884 - 1080 WP_264678019.1 3-deoxy-7-phosphoheptulonate synthase -
LP095_RS04005 (LP095_04005) 762091..762333 + 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP095_RS04010 (LP095_04010) 762333..762668 + 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP095_RS04015 (LP095_04015) 762730..763725 + 996 WP_208624081.1 polyprenyl synthetase family protein -
LP095_RS04020 (LP095_04020) 763749..763985 + 237 WP_264678020.1 hypothetical protein -
LP095_RS04025 (LP095_04025) 764075..766219 - 2145 WP_264678021.1 cation-translocating P-type ATPase -
LP095_RS04030 (LP095_04030) 766486..766914 - 429 WP_268194266.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T263099 WP_078275234.1 NZ_CP110087:762333-762668 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT263099 WP_078275235.1 NZ_CP110087:762091-762333 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References