Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 643927..644576 Replicon chromosome
Accession NZ_CP110087
Organism Moraxella bovis strain SAM109242

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LP095_RS03370 Protein ID WP_264677937.1
Coordinates 644175..644576 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LP095_RS03365 Protein ID WP_112741908.1
Coordinates 643927..644160 (+) Length 78 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP095_RS03345 (LP095_03345) 639323..639772 - 450 WP_264683685.1 cytochrome c -
LP095_RS03350 (LP095_03350) 639954..640946 - 993 WP_264683684.1 oxygen-dependent coproporphyrinogen oxidase -
LP095_RS03355 (LP095_03355) 640966..641559 - 594 WP_208624078.1 GTP cyclohydrolase II -
LP095_RS03360 (LP095_03360) 641780..643879 + 2100 WP_264683682.1 1-deoxy-D-xylulose-5-phosphate synthase -
LP095_RS03365 (LP095_03365) 643927..644160 + 234 WP_112741908.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
LP095_RS03370 (LP095_03370) 644175..644576 + 402 WP_264677937.1 type II toxin-antitoxin system VapC family toxin Toxin
LP095_RS03375 (LP095_03375) 645100..645600 + 501 WP_112741909.1 WG repeat-containing protein -
LP095_RS03380 (LP095_03380) 645722..646552 + 831 WP_264677938.1 inositol monophosphatase family protein -
LP095_RS03385 (LP095_03385) 646652..647341 - 690 WP_264677939.1 SIMPL domain-containing protein -
LP095_RS03395 (LP095_03395) 648079..648498 - 420 WP_264677940.1 S4 domain-containing protein -
LP095_RS03400 (LP095_03400) 648750..648923 - 174 WP_264677941.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-125)

Antitoxin

(8-54)


Sequences


Toxin        


Download         Length: 134 a.a.        Molecular weight: 15071.29 Da        Isoelectric Point: 6.8426

>T263098 WP_264677937.1 NZ_CP110087:644175-644576 [Moraxella bovis]
MFSFMLDTNICIYVIKERPIKALNKFNQYAGRICVSSIVASELYFGAYNSQFMDKNLHQVEDFLSRLTVLDYTAECSPHY
GEICADLTKQGKLISENDIHIASHARALGLTLITNNTDEFKRVSGLRIGNWAI

Download         Length: 402 bp


Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8990.22 Da        Isoelectric Point: 6.2884

>AT263098 WP_112741908.1 NZ_CP110087:643927-644160 [Moraxella bovis]
MQTSVFFNNRTQAVRIPAKFRFDDDVKAVMIRKVGNERILTPIDGVWDSFFLSDERASDDFMANRPTMPKSERLTFD

Download         Length: 234 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References