Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataT-KacA/DUF1778(antitoxin)
Location 25369..26163 Replicon plasmid p1WJP83
Accession NZ_CP110081
Organism Buttiauxella sp. WJP83

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag OH773_RS21870 Protein ID WP_270146300.1
Coordinates 25369..25890 (-) Length 174 a.a.

Antitoxin (Protein)


Gene name KacA Uniprot ID -
Locus tag OH773_RS21875 Protein ID WP_270146302.1
Coordinates 25894..26163 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH773_RS21840 (OH773_21840) 22121..22702 + 582 WP_270146287.1 tail fiber assembly protein -
OH773_RS21845 (OH773_21845) 22777..23100 + 324 WP_270146289.1 hypothetical protein -
OH773_RS21850 (OH773_21850) 23112..23804 + 693 WP_270146291.1 hypothetical protein -
OH773_RS21855 (OH773_21855) 23806..24057 + 252 WP_270146293.1 hypothetical protein -
OH773_RS21860 (OH773_21860) 24050..24214 + 165 WP_270146295.1 hypothetical protein -
OH773_RS21865 (OH773_21865) 24391..25227 + 837 WP_270146297.1 restriction endonuclease -
OH773_RS21870 (OH773_21870) 25369..25890 - 522 WP_270146300.1 GNAT family N-acetyltransferase Toxin
OH773_RS21875 (OH773_21875) 25894..26163 - 270 WP_270146302.1 DUF1778 domain-containing protein Antitoxin
OH773_RS21880 (OH773_21880) 26487..27152 + 666 WP_270146304.1 AAA family ATPase -
OH773_RS21885 (OH773_21885) 27158..27511 + 354 WP_270146377.1 hypothetical protein -
OH773_RS21890 (OH773_21890) 27555..28349 - 795 WP_270146306.1 DUF2971 domain-containing protein -
OH773_RS21895 (OH773_21895) 28619..29344 + 726 WP_270146308.1 hypothetical protein -
OH773_RS21900 (OH773_21900) 29405..30745 + 1341 WP_270146310.1 DnaB-like helicase C-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..111544 111544


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-149)

Antitoxin

Vibrio phage ICP1, Orf50

(3-88)


Sequences

Toxin        


Download         Length: 174 a.a.        Molecular weight: 19272.98 Da        Isoelectric Point: 6.9681

>T263096 WP_270146300.1 NZ_CP110081:c25890-25369 [Buttiauxella sp. WJP83]
VADLTIEIFSEGNEYDFSDFDCGEESLNVFLTDHLARQHSGRILRGYLLLTKDPKPKVLGYYTLSGSCFEKATLPSKTQQ
RKVPYSNVPSVTLGRLAVHKDLQGKEWGTTLVTHAMKVVYSASLAVGVHGMFVDALNDGAKRFYTKLGFIPLVGDNTNSL
FYPTKSIEKLFEE

Download         Length: 522 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10152.61 Da        Isoelectric Point: 7.0150

>AT263096 WP_270146302.1 NZ_CP110081:c26163-25894 [Buttiauxella sp. WJP83]
MSALKKQRIDLRLTDDDKSMIEEAAAMSNQTITQFMVASASERAAEVIEQHRRLILNEQSWNLVMDAISNPPAPNDRLKR
AAKRLQNME

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References