Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3524962..3525617 Replicon chromosome
Accession NZ_CP110080
Organism Buttiauxella sp. WJP83

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OH773_RS16325 Protein ID WP_270145917.1
Coordinates 3524962..3525354 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OH773_RS16330 Protein ID WP_270140035.1
Coordinates 3525354..3525617 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH773_RS16295 (OH773_16295) 3520509..3521294 + 786 WP_270140024.1 transcriptional regulator LldR -
OH773_RS16300 (OH773_16300) 3521291..3522472 + 1182 WP_270140026.1 FMN-dependent L-lactate dehydrogenase LldD -
OH773_RS16305 (OH773_16305) 3522535..3522963 - 429 WP_270140028.1 OsmC family protein -
OH773_RS16310 (OH773_16310) 3523122..3523655 + 534 WP_270140030.1 tetratricopeptide repeat protein -
OH773_RS16315 (OH773_16315) 3523745..3524194 + 450 WP_270145915.1 RNA polymerase sigma factor -
OH773_RS16320 (OH773_16320) 3524191..3524934 + 744 WP_270140032.1 anti-sigma factor -
OH773_RS16325 (OH773_16325) 3524962..3525354 - 393 WP_270145917.1 type II toxin-antitoxin system VapC family toxin Toxin
OH773_RS16330 (OH773_16330) 3525354..3525617 - 264 WP_270140035.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
OH773_RS16335 (OH773_16335) 3525887..3526168 - 282 WP_270140037.1 acetolactate synthase small subunit -
OH773_RS16340 (OH773_16340) 3526172..3527860 - 1689 WP_270140039.1 acetolactate synthase large subunit -
OH773_RS16345 (OH773_16345) 3527972..3528070 - 99 WP_183271233.1 ilvB operon leader peptide IvbL -
OH773_RS16350 (OH773_16350) 3528200..3529222 - 1023 WP_270140042.1 GTP-binding protein -
OH773_RS16355 (OH773_16355) 3529238..3529435 - 198 WP_034456870.1 YbdD/YjiX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14270.49 Da        Isoelectric Point: 8.4392

>T263093 WP_270145917.1 NZ_CP110080:c3525354-3524962 [Buttiauxella sp. WJP83]
MAYMLDTNTVSYFLRQHPQIVARISAVPPSSISISSITEAELLFGVEKRRNKALKTAVMGFLDAVSIYEWDSAAAQTYGK
LRASMEKKGHVMGALDMLIAAHALSEKTTLITSDRAFYGVAGLQVQDWTV

Download         Length: 393 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10122.50 Da        Isoelectric Point: 9.7634

>AT263093 WP_270140035.1 NZ_CP110080:c3525617-3525354 [Buttiauxella sp. WJP83]
MERIAKLFKNGRNQAVRLPVEFEFDTDRVYIRQDKEGNVILSKRPAKPDNWDNVISLIKKARVPDNFLDAEERNQPPADR
DPFAGIK

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References