Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 776350..777019 Replicon chromosome
Accession NZ_CP110080
Organism Buttiauxella sp. WJP83

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OH773_RS03675 Protein ID WP_270143122.1
Coordinates 776597..777019 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1B7I271
Locus tag OH773_RS03670 Protein ID WP_064513590.1
Coordinates 776350..776616 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH773_RS03650 (OH773_03650) 771773..773206 - 1434 WP_270143113.1 6-phospho-beta-glucosidase -
OH773_RS03655 (OH773_03655) 773372..774100 - 729 WP_183270561.1 MurR/RpiR family transcriptional regulator -
OH773_RS03660 (OH773_03660) 774292..774945 + 654 WP_270143116.1 hemolysin III family protein -
OH773_RS03665 (OH773_03665) 774988..775977 - 990 WP_270143118.1 tRNA-modifying protein YgfZ -
OH773_RS03670 (OH773_03670) 776350..776616 + 267 WP_064513590.1 FAD assembly factor SdhE Antitoxin
OH773_RS03675 (OH773_03675) 776597..777019 + 423 WP_270143122.1 protein YgfX Toxin
OH773_RS03680 (OH773_03680) 777027..777548 - 522 WP_183270557.1 flavodoxin FldB -
OH773_RS03685 (OH773_03685) 777684..778580 + 897 WP_270143124.1 site-specific tyrosine recombinase XerD -
OH773_RS03690 (OH773_03690) 778605..779321 + 717 WP_270143126.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OH773_RS03695 (OH773_03695) 779329..781062 + 1734 WP_270143128.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16688.71 Da        Isoelectric Point: 10.8200

>T263085 WP_270143122.1 NZ_CP110080:776597-777019 [Buttiauxella sp. WJP83]
VVLWQSDLRVSWRAQWISLLVHGMIALFVLLMPWPMSYTLIWMLLLSLVVFDSVRSQRRIHACQGEMKLLTDYHLRWQNQ
EWEIVGAPWVLRSGMMLRLRRLGRKRCQHLWLSADSMDIGEWRDLRRLMQQQQASGSGEV

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10471.97 Da        Isoelectric Point: 5.1238

>AT263085 WP_064513590.1 NZ_CP110080:776350-776616 [Buttiauxella sp. WJP83]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSTEDKQLFVRLLESDDPDLFNWLMNHGKPADTELQRMVTLIQTRN
KERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1B7I271

References