Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mazEF/PRK09907(toxin) |
Location | 264914..265485 | Replicon | chromosome |
Accession | NZ_CP110071 | ||
Organism | Enterococcus faecalis strain BE8 |
Toxin (Protein)
Gene name | mazF | Uniprot ID | - |
Locus tag | OLL94_RS01250 | Protein ID | WP_002354774.1 |
Coordinates | 265144..265485 (+) | Length | 114 a.a. |
Antitoxin (Protein)
Gene name | mazE | Uniprot ID | R3JGB1 |
Locus tag | OLL94_RS01245 | Protein ID | WP_002354773.1 |
Coordinates | 264914..265144 (+) | Length | 77 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OLL94_RS01225 (260288) | 260288..261904 | - | 1617 | WP_002378864.1 | phosphatase PAP2/LCP family protein | - |
OLL94_RS01230 (262589) | 262589..263227 | + | 639 | WP_002378863.1 | lytic polysaccharide monooxygenase | - |
OLL94_RS01235 (263394) | 263394..264386 | - | 993 | WP_002378862.1 | biotin--[acetyl-CoA-carboxylase] ligase | - |
OLL94_RS01240 (264525) | 264525..264740 | + | 216 | WP_002354768.1 | zinc ribbon domain-containing protein | - |
OLL94_RS01245 (264914) | 264914..265144 | + | 231 | WP_002354773.1 | hypothetical protein | Antitoxin |
OLL94_RS01250 (265144) | 265144..265485 | + | 342 | WP_002354774.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
OLL94_RS01255 (265856) | 265856..269470 | + | 3615 | WP_002389470.1 | DNA-directed RNA polymerase subunit beta | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 114 a.a. Molecular weight: 13156.40 Da Isoelectric Point: 9.3984
>T263029 WP_002354774.1 NZ_CP110071:265144-265485 [Enterococcus faecalis]
MNVEKKYIPKKGDIVWIDFDPAAGKEIQKRRPGLVVSRYEFNRKTMFAVICPITSTIKNIPTRYTLPDDIETQGQVVISQ
LKSLDFTERKLSQIEHLPLKDMAKIDQIIEYIF
MNVEKKYIPKKGDIVWIDFDPAAGKEIQKRRPGLVVSRYEFNRKTMFAVICPITSTIKNIPTRYTLPDDIETQGQVVISQ
LKSLDFTERKLSQIEHLPLKDMAKIDQIIEYIF
Download Length: 342 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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