262987

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) omega-epsilon-zeta/zeta-epsilon
Location 22951..24088 Replicon plasmid pBE15_3
Accession NZ_CP110066
Organism Enterococcus faecalis strain BE15

Toxin (Protein)


Gene name zeta Uniprot ID -
Locus tag OLL96_RS14810 Protein ID WP_264526513.1
Coordinates 22951..23814 (-) Length 288 a.a.

Antitoxin (Protein)


Gene name epsilon Uniprot ID -
Locus tag OLL96_RS14815 Protein ID WP_115253291.1
Coordinates 23816..24088 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLL96_RS14775 (OLL96_14775) 18122..18454 - 333 WP_000713503.1 CagC family type IV secretion system protein -
OLL96_RS14780 (OLL96_14780) 18478..20472 - 1995 WP_264526509.1 MobA/MobL family protein -
OLL96_RS14785 (OLL96_14785) 20755..21054 + 300 WP_264560705.1 hypothetical protein -
OLL96_RS14790 (OLL96_14790) 21057..21329 + 273 WP_264560706.1 hypothetical protein -
OLL96_RS14795 (OLL96_14795) 21336..21641 - 306 WP_264526512.1 hypothetical protein -
OLL96_RS14800 (OLL96_14800) 21675..22172 - 498 WP_002300565.1 molecular chaperone DnaJ -
OLL96_RS14805 (OLL96_14805) 22192..22509 - 318 WP_002338433.1 hypothetical protein -
OLL96_RS14810 (OLL96_14810) 22951..23814 - 864 WP_264526513.1 zeta toxin family protein Toxin
OLL96_RS14815 (OLL96_14815) 23816..24088 - 273 WP_115253291.1 antitoxin Antitoxin
OLL96_RS14820 (OLL96_14820) 24106..24321 - 216 WP_001835296.1 peptide-binding protein -
OLL96_RS14825 (OLL96_14825) 24413..25267 - 855 WP_264526514.1 ParA family protein -
OLL96_RS14830 (OLL96_14830) 25413..27557 - 2145 WP_264526515.1 type IA DNA topoisomerase -
OLL96_RS14835 (OLL96_14835) 27557..28174 - 618 WP_001062589.1 recombinase family protein -
OLL96_RS14840 (OLL96_14840) 28188..28358 - 171 WP_000713595.1 hypothetical protein -
OLL96_RS14845 (OLL96_14845) 28455..28799 - 345 WP_264526516.1 MerR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..28923 28923


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Zeta toxin domain

(23-214)

Antitoxin

Bacterial epsilon antitoxin

(2-90)


Sequences

Toxin        


Download         Length: 288 a.a.        Molecular weight: 32431.09 Da        Isoelectric Point: 6.9964

>T262987 WP_264526513.1 NZ_CP110066:c23814-22951 [Enterococcus faecalis]
MANIVNFTDKQFENRLNDNLEELLQGKKAVESPTAFLLGGQPGSGKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELV
KLYEKDVVKHVTPYSNRMTEAIISRLSDQGYSLVIEGTGRTTDVPIQTATMLQAKGYETKMYVMAVPKINSYLGTIERYE
TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETPSISPKETLERELNRKVSGKEIQ
PTLERIEQKMILNKHQETPEFKAIQQKLESLQPPTPPIPKIPKLPGI

Download         Length: 864 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10719.27 Da        Isoelectric Point: 6.4676

>AT262987 WP_115253291.1 NZ_CP110066:c24088-23816 [Enterococcus faecalis]
MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELNKNDSQLLEVNLLNQLKLAKRVNLFDYSLEELQAIHEYWRAMNRYS
KQVLNKEKVA

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References