Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907(toxin)
Location 2752408..2752979 Replicon chromosome
Accession NZ_CP110059
Organism Enterococcus faecalis strain BE16

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag OLL92_RS13410 Protein ID WP_002354774.1
Coordinates 2752408..2752749 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag OLL92_RS13415 Protein ID WP_104875562.1
Coordinates 2752749..2752979 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLL92_RS13405 (2748423) 2748423..2752037 - 3615 WP_002389470.1 DNA-directed RNA polymerase subunit beta -
OLL92_RS13410 (2752408) 2752408..2752749 - 342 WP_002354774.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
OLL92_RS13415 (2752749) 2752749..2752979 - 231 WP_104875562.1 AbrB family transcriptional regulator Antitoxin
OLL92_RS13420 (2753386) 2753386..2753601 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
OLL92_RS13425 (2753740) 2753740..2754732 + 993 WP_002358973.1 biotin--[acetyl-CoA-carboxylase] ligase -
OLL92_RS13430 (2754799) 2754799..2755431 - 633 WP_002358972.1 RloB family protein -
OLL92_RS13435 (2755440) 2755440..2756735 - 1296 WP_010820355.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(7-112)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13156.40 Da        Isoelectric Point: 9.3984

>T262944 WP_002354774.1 NZ_CP110059:c2752749-2752408 [Enterococcus faecalis]
MNVEKKYIPKKGDIVWIDFDPAAGKEIQKRRPGLVVSRYEFNRKTMFAVICPITSTIKNIPTRYTLPDDIETQGQVVISQ
LKSLDFTERKLSQIEHLPLKDMAKIDQIIEYIF

Download         Length: 342 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8703.70 Da        Isoelectric Point: 4.2092

>AT262944 WP_104875562.1 NZ_CP110059:c2752979-2752749 [Enterococcus faecalis]
MLTTKSRRQGSSVVLTLPTDNGKKPKVDQEYIVMYSDDGTITLVPKIQDPFSEGPEGEYYEKDEWYDLAPEGRELF

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References