Detailed information of TA system TA026287

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 158656..159233
• Replicon: plasmid pAPA07-010
• Accession: NC_017143
• Organism: Acetobacter pasteurianus IFO 3283-07

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: C7JIL1
• Locus tag: APA07_RS14395
• Protein ID: WP_006115553.1
• Coordinates: 158656..158964 (-)
• Length: 103 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: C7JIL2
• Locus tag: APA07_RS14400
• Protein ID: WP_006115552.1
• Coordinates: 158961..159233 (-)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
APA07_RS16220	153789..154007	-	219	WP_170315285.1	WGR domain-containing protein	-
APA07_RS14345	154086..154364	-	279	WP_006115563.1	HU family DNA-binding protein	-
APA07_RS16670	155806..155991	-	186	WP_041633309.1	hypothetical protein	-
APA07_RS14365	156076..156891	+	816	WP_012813210.1	hypothetical protein	-
APA07_RS14370	156904..157308	+	405	WP_006115557.1	hypothetical protein	-
APA07_RS14375	157365..157685	-	321	WP_012813211.1	hypothetical protein	-
APA07_RS14380	157715..157915	-	201	WP_012813212.1	hypothetical protein	-
APA07_RS14385	157972..158301	-	330	WP_012813213.1	endoribonuclease MazF	-
APA07_RS14390	158303..158557	-	255	WP_006115554.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-
APA07_RS14395	158656..158964	-	309	WP_006115553.1	PIN domain-containing protein	Toxin
APA07_RS14400	158961..159233	-	273	WP_006115552.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
APA07_RS14405	159563..159934	-	372	Protein_154	integrase core domain-containing protein	-
APA07_RS14410	160028..161413	+	1386	WP_012813126.1	IS1380-like element IS1380A family transposase	-
APA07_RS16235	161545..161996	+	452	Protein_156	recombinase family protein	-
APA07_RS14415	162310..163083	-	774	WP_003631418.1	TSUP family transporter	-
APA07_RS14420	163275..163859	+	585	Protein_158	IS701 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..191427	191427

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Antitoxin

• Toxin YoeB (5-84)

Sequences

Toxin

Protein

• Length: 103 a.a.
• Molecular weight: 15177.21 Da
• Isoelectric Point: 5.5500

>T26287 WP_006115553.1 NC_017143:c158964-158656 [Acetobacter pasteurianus IFO 3283-07]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 309 bp

>T26287 NC_017143:c158964-158656 [Acetobacter pasteurianus IFO 3283-07]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 13411.09 Da
• Isoelectric Point: 5.5500

>AT26287 WP_006115552.1 NC_017143:c159233-158961 [Acetobacter pasteurianus IFO 3283-07]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFF

Nucleotide

• Length: 273 bp

>AT26287 NC_017143:c159233-158961 [Acetobacter pasteurianus IFO 3283-07]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Structures

Toxin

• AlphaFold DB: A0A401X8Y0

Antitoxin

• AlphaFold DB: A0A401X8Q2