Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-VagC |
Location | 158648..159225 | Replicon | plasmid pAPA26-013 |
Accession | NC_017130 | ||
Organism | Acetobacter pasteurianus IFO 3283-26 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | C7JIL1 |
Locus tag | APA26_RS14400 | Protein ID | WP_006115553.1 |
Coordinates | 158648..158956 (-) | Length | 103 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | C7JIL2 |
Locus tag | APA26_RS14405 | Protein ID | WP_006115552.1 |
Coordinates | 158953..159225 (-) | Length | 91 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
APA26_RS16215 | 153781..153999 | - | 219 | WP_170315285.1 | WGR domain-containing protein | - |
APA26_RS14350 | 154078..154356 | - | 279 | WP_006115563.1 | HU family DNA-binding protein | - |
APA26_RS16680 | 155798..155983 | - | 186 | WP_041633309.1 | hypothetical protein | - |
APA26_RS14370 | 156068..156883 | + | 816 | WP_012813210.1 | hypothetical protein | - |
APA26_RS14375 | 156896..157300 | + | 405 | WP_006115557.1 | hypothetical protein | - |
APA26_RS14380 | 157357..157677 | - | 321 | WP_012813211.1 | hypothetical protein | - |
APA26_RS14385 | 157707..157907 | - | 201 | WP_012813212.1 | hypothetical protein | - |
APA26_RS14390 | 157964..158293 | - | 330 | WP_012813213.1 | endoribonuclease MazF | - |
APA26_RS14395 | 158295..158549 | - | 255 | WP_006115554.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
APA26_RS14400 | 158648..158956 | - | 309 | WP_006115553.1 | PIN domain-containing protein | Toxin |
APA26_RS14405 | 158953..159225 | - | 273 | WP_006115552.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
APA26_RS14410 | 159555..159926 | - | 372 | Protein_154 | integrase core domain-containing protein | - |
APA26_RS14415 | 160020..161405 | + | 1386 | WP_012813126.1 | IS1380-like element IS1380A family transposase | - |
APA26_RS16230 | 161537..161988 | + | 452 | Protein_156 | recombinase family protein | - |
APA26_RS14420 | 162302..163075 | - | 774 | WP_003631418.1 | TSUP family transporter | - |
APA26_RS14425 | 163267..163851 | + | 585 | Protein_158 | IS701 family transposase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..191419 | 191419 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 a.a. Molecular weight: 15177.21 Da Isoelectric Point: 5.5500
>T26273 WP_006115553.1 NC_017130:c158956-158648 [Acetobacter pasteurianus IFO 3283-26]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFF
Download Length: 309 bp
>T26273 NC_017130:c158956-158648 [Acetobacter pasteurianus IFO 3283-26]
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Antitoxin
Download Length: 91 a.a. Molecular weight: 13411.09 Da Isoelectric Point: 5.5500
>AT26273 WP_006115552.1 NC_017130:c159225-158953 [Acetobacter pasteurianus IFO 3283-26]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFF
Download Length: 273 bp
>AT26273 NC_017130:c159225-158953 [Acetobacter pasteurianus IFO 3283-26]
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Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A401X8Y0 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A401X8Q2 |