Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 158648..159225 Replicon plasmid pAPA26-013
Accession NC_017130
Organism Acetobacter pasteurianus IFO 3283-26

Toxin (Protein)


Gene name vapC Uniprot ID C7JIL1
Locus tag APA26_RS14400 Protein ID WP_006115553.1
Coordinates 158648..158956 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID C7JIL2
Locus tag APA26_RS14405 Protein ID WP_006115552.1
Coordinates 158953..159225 (-) Length 91 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
APA26_RS16215 153781..153999 - 219 WP_170315285.1 WGR domain-containing protein -
APA26_RS14350 154078..154356 - 279 WP_006115563.1 HU family DNA-binding protein -
APA26_RS16680 155798..155983 - 186 WP_041633309.1 hypothetical protein -
APA26_RS14370 156068..156883 + 816 WP_012813210.1 hypothetical protein -
APA26_RS14375 156896..157300 + 405 WP_006115557.1 hypothetical protein -
APA26_RS14380 157357..157677 - 321 WP_012813211.1 hypothetical protein -
APA26_RS14385 157707..157907 - 201 WP_012813212.1 hypothetical protein -
APA26_RS14390 157964..158293 - 330 WP_012813213.1 endoribonuclease MazF -
APA26_RS14395 158295..158549 - 255 WP_006115554.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
APA26_RS14400 158648..158956 - 309 WP_006115553.1 PIN domain-containing protein Toxin
APA26_RS14405 158953..159225 - 273 WP_006115552.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
APA26_RS14410 159555..159926 - 372 Protein_154 integrase core domain-containing protein -
APA26_RS14415 160020..161405 + 1386 WP_012813126.1 IS1380-like element IS1380A family transposase -
APA26_RS16230 161537..161988 + 452 Protein_156 recombinase family protein -
APA26_RS14420 162302..163075 - 774 WP_003631418.1 TSUP family transporter -
APA26_RS14425 163267..163851 + 585 Protein_158 IS701 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..191419 191419


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-84)

Antitoxin

(1-73)


Sequences


Toxin        


Download         Length: 103 a.a.        Molecular weight: 15177.21 Da        Isoelectric Point: 5.5500

>T26273 WP_006115553.1 NC_017130:c158956-158648 [Acetobacter pasteurianus IFO 3283-26]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 309 bp

>T26273 NC_017130:c158956-158648 [Acetobacter pasteurianus IFO 3283-26]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 13411.09 Da        Isoelectric Point: 5.5500

>AT26273 WP_006115552.1 NC_017130:c159225-158953 [Acetobacter pasteurianus IFO 3283-26]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFF

Download         Length: 273 bp

>AT26273 NC_017130:c159225-158953 [Acetobacter pasteurianus IFO 3283-26]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A401X8Y0


Antitoxin

Source ID Structure
AlphaFold DB A0A401X8Q2

References